A4IJH7 (RL1_GEOTN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L1

Gene names

Name:	rplA
Ordered Locus Names:	GTNG_0094

Organism

Geobacillus thermodenitrificans (strain NG80-2) [Complete proteome] [HAMAP]

Taxonomic identifier

420246 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity. HAMAP MF_01318_B Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity. HAMAP MF_01318_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L1P family.

Ontologies

Keywords
Biological process	Translation regulation
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Repressor Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of translation Inferred from electronic annotation. Source: UniProtKB-KW translation Inferred from electronic annotation. Source: InterPro
Cellular component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 233	233	50S ribosomal protein L1 HAMAP MF_01318_B		PRO_0000308013

Sequences

	Sequence		Length	Mass (Da)
	A4IJH7 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: 113CD48D992A5954	FASTA	233	25,090
	10 20 30 40 50 60 MPKRGKKYLE ALKLVDRFKA YPVAEAIELV KKTNVAKFDA TVEVAFRLGV DPKKADQQIR 70 80 90 100 110 120 GAVVLPHGTG KVARVLVFAK GEKAKEAEAA GADYVGDTEY INKIQQGWFD FDVVVATPDM 130 140 150 160 170 180 MGEVGKLGRI LGPKGLMPNP KTGTVTFDVT KAVQEIKAGK VEYRVDKAGN IHVPIGKVSF 190 200 210 220 230 DNEKLAENFA TIYEAILKAK PAAAKGTYVK NVTITSTMGP GIKVDPTTVA VAQ

References

[1]

"Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir." Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L. Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007) [PubMed: 17372208] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NG80-2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000557 Genomic DNA. Translation: ABO65481.1.
RefSeq	YP_001124226.1. NC_009328.1.
3D structure databases
ProteinModelPortal	A4IJH7.
SMR	A4IJH7. Positions 6-227.
ModBase	Search...
Protein-protein interaction databases
STRING	A4IJH7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4965220.
GenomeReviews	Gene locus GTNG_0094 in contig CP000557_GR.
KEGG	gtn:GTNG_0094.
NMPDR	fig|420246.5.peg.93.
PATRIC	21976327. VBIGeoThe136879_0099.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0081.
HOGENOM	HBG297400.
OMA	KAGTVTM.
PhylomeDB	A4IJH7.
ProtClustDB	PRK05424.
Enzyme and pathway databases
BioCyc	GTHE420246:GTNG_0094-MONOMER.
Family and domain databases
HAMAP	MF_01318_B. Ribosomal_L1_B. [Tree]
InterPro	IPR005878. Ribosom_L1_bac-type. IPR002143. Ribosomal_L1. IPR016094. Ribosomal_L1_2-a/b-sand. IPR016095. Ribosomal_L1_3-a/b-sand. IPR023673. Ribosomal_L1_CS. IPR023674. Ribosomal_L1_SF. [Graphical view]
Gene3D	G3DSA:3.30.190.20. Ribosomal_L1_2-a/b-sand. 2 hits. G3DSA:3.40.50.790. Ribosomal_L1_3-a/b-sand. 1 hit.
KO	K02863.
Pfam	PF00687. Ribosomal_L1. 1 hit. [Graphical view]
PIRSF	PIRSF002155. Ribosomal_L1. 1 hit.
SUPFAM	SSF56808. Ribosomal_L1. 1 hit.
TIGRFAMs	TIGR01169. RplA_bact. 1 hit.
PROSITE	PS01199. RIBOSOMAL_L1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL1_GEOTN

Accession

Primary (citable) accession number: A4IJH7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
Last sequence update:	May 1, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program