A4IJE8 (A4IJE8_GEOTN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Ordered Locus Names:

GTNG_0065

Organism

Geobacillus thermodenitrificans (strain NG80-2) [Complete proteome] [HAMAP]

Taxonomic identifier

420246 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Transferase RuleBase RU003985
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4IJE8 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: 25BA67CB99C8B51B	FASTA	308	32,545
	10 20 30 40 50 60 MARTVNSVTE LIGDTPAVKL NRIVDEDSAD VYVKLEFMNP GSSVKDRIAL AMIEAAEKAG 70 80 90 100 110 120 RLKPGDTIVE PTSGNTGIGL AMVAAAKGYK AVLVMPDTMS LERRNLLRAY GAELVLTPGA 130 140 150 160 170 180 QGMRGAIQKA EELAREHGYF MPQQFKNEAN PEIHRLTTGK EIVEQMGDQL DAFVAGIGTG 190 200 210 220 230 240 GTITGAGKVL REAYPNIKIY AVEPADSPVL SGGKPGPHKI QGIGAGFVPD ILDTSIYDGV 250 260 270 280 290 300 ITVTTEEAFA AARRAAREEG ILGGISSGAA IHAALKVAKE LGKGKKVLAV IPSNGERYLS TPLYQFEN

References

[1]

"Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir." Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X., Han W., Peng X., Liu R., Wang L. Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007) [PubMed: 17372208] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000557 Genomic DNA. Translation: ABO65452.1.
RefSeq	YP_001124197.1. NC_009328.1.
3D structure databases
ProteinModelPortal	A4IJE8.
SMR	A4IJE8. Positions 1-308.
ModBase	Search...
Protein-protein interaction databases
STRING	A4IJE8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4965191.
GenomeReviews	Gene locus GTNG_0065 in contig CP000557_GR.
KEGG	gtn:GTNG_0065.
NMPDR	fig|420246.5.peg.65.
PATRIC	21976245. VBIGeoThe136879_0070.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0031.
HOGENOM	HBG748215.
OMA	SAGANIH.
PhylomeDB	A4IJE8.
ProtClustDB	CLSK712444.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR005856. Cys_synthKM. IPR005859. CysK. IPR001926. PyrdxlP-dep_enz_bsu. [Graphical view]
KO	K01738.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMs	TIGR01139. CysK. 1 hit. TIGR01136. CysKM. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4IJE8_GEOTN

Accession

Primary (citable) accession number: A4IJE8

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)