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Protein
Submitted name:

Hk1 protein

Gene

hk1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hk1 proteinImported
Gene namesi
Name:hk1Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-944850. hk1.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PaxDbiA4II49.

Structurei

3D structure databases

ProteinModelPortaliA4II49.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 219Hexokinase_1InterPro annotationAdd BLAST198
Domaini225 – 459Hexokinase_2InterPro annotationAdd BLAST235
Domaini470 – 667Hexokinase_1InterPro annotationAdd BLAST198
Domaini673 – 907Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
HOGENOMiHOG000162671.
HOVERGENiHBG005020.
KOiK00844.
OrthoDBiEOG091G08MD.

Family and domain databases

InterProiView protein in InterPro
IPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiView protein in Pfam
PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
PROSITEiView protein in PROSITE
PS00378. HEXOKINASE_1. 2 hits.
PS51748. HEXOKINASE_2. 2 hits.

Sequencei

Sequence statusi: Complete.

A4II49-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAAQLLAYY FTELKDDQLK KIDKYLYSMR LSDETLLDIM GRFRAEMANG
60 70 80 90 100
LSRDTNPTAI IKMLPTFVRS IPDGTEKGDF IALDLGGSHF RILRVKVSHE
110 120 130 140 150
KKQTVQMESE IYDTPEDIIH GSGTRLFDHV AECLGDFMQK KQIKDKKLPV
160 170 180 190 200
GFTFSFPCIQ TKIDEGVLVT WTKRFKASGV EGMDVVKLLN KAIKKRGDYE
210 220 230 240 250
ADIMAVVNDT VGTMMTCGFD DQRCEVGIII GTGTNACYME ELRHIDMVEG
260 270 280 290 300
DEGRMCINTE WGAFGDDGCL EDIRSEFDRE IDRGSLNPGK QLFEKMVSGM
310 320 330 340 350
YMGELVRLIL VKMAKEGLLF EGRITPELLT RGKFETKHVS AIEKSKEGLS
360 370 380 390 400
KAKDILTRLG VEPSHEDCIA VQHVCTIVSF RSANLVAATL GGILIRLRDN
410 420 430 440 450
KGVPRLRTTV GIDGSLYKMH PQYARRLHKT VRRLVPESDV RFLLSESGSG
460 470 480 490 500
KGAAMVTAVA YRLSEQRRQI DETLEEFKLS REQLLEVKRR MRIEIENGLR
510 520 530 540 550
KKTHESAKVK MLPTYVRSTP DGTENGDFLA LDLGGTNFRV LLVKIRSGKR
560 570 580 590 600
RTVEMHNKIY AIPIDVMQGT GEELFDHIAH CISDFLDYMG IKGARLPLGF
610 620 630 640 650
TFSFPCMQTS LDAGILVTWT KGFKATDCEG EDVVNLLREG IKRREEFDLD
660 670 680 690 700
VVAIVNDTVG TMMTCAYEDP NCEIGLIVGT GSNACYMEET KNIEMVDGDQ
710 720 730 740 750
GRMCVNMEWG AFGDNGCLDD IRTVYDKAVD DLSLNSGKQR YEKMISGMYL
760 770 780 790 800
GEIVRNILID FTKRGFLFRG QISEALKTTS IFETKFLSQI ESDRLALLQV
810 820 830 840 850
RSILQQLGLN STCDDSIIVK EVCGAVSRRA AQVCGAGMAA VVDKIRENRG
860 870 880 890 900
LDHLDVTVGV DGTLYKLHPH FSKIMHQTVK DLAPKCNVSF LLSEDGSGKG
910
AALITAVACR LRSSEQN
Length:917
Mass (Da):102,488
Last modified:May 1, 2007 - v1
Checksum:i6EDA889A27F75BE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC135849 mRNA. Translation: AAI35850.1.
RefSeqiNP_001096201.1. NM_001102731.1.
UniGeneiStr.64346.

Genome annotation databases

GeneIDi100124752.
KEGGixtr:100124752.

Similar proteinsi

Entry informationi

Entry nameiA4II49_XENTR
AccessioniPrimary (citable) accession number: A4II49
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: August 30, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)