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Protein

One cut domain family member

Gene

onecut1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
One cut domain family memberUniRule annotation
Gene namesi
Name:onecut1Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-480152. onecut1.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiA4II00.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000013904.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2D5VX-ray2.00A/B282-472[»]
ProteinModelPortaliA4II00.
SMRiA4II00. Positions 284-465.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini276 – 36287CUT DNA-bindingInterPro annotationAdd
BLAST
Domaini411 – 47161Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the CUT homeobox family.UniRule annotation
Contains 1 CUT DNA-binding domain.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation

Keywords - Domaini

HomeoboxUniRule annotation

Phylogenomic databases

eggNOGiKOG2252. Eukaryota.
ENOG410YWY4. LUCA.
HOVERGENiHBG005981.
KOiK08026.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR003350. CUT_dom.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF02376. CUT. 1 hit.
PF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM01109. CUT. 1 hit.
SM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS51042. CUT. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4II00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAQLTMDAI GDLHGISHES VPGTADLMGS SPHHRGSVTH RSNHLSAHPR
60 70 80 90 100
SMGMASILDG GDYHHHHHHH HRPPDHALTG PLHPTMTMAC DTPPGMSMSS
110 120 130 140 150
TYTTLTPLQP LPPISTVSDK FPHHHHHHHP HQRIPGNVSG SFTLMRDDRG
160 170 180 190 200
LASMNNLYSP YHKEVTGMGQ SLSPLSGSGL GSIHGAQQGP PHYAHPSAAM
210 220 230 240 250
PTEKMLTPNG FEAHHPAMLT RHGEQHLTPP SAGMVPINGI PHHPHAHLNA
260 270 280 290 300
QSHGQILAST RDQNPPSVTG SQINNGSNSG QMEEINTKEV AQRITTELKR
310 320 330 340 350
YSIPQAIFAQ RVLCRSQGTL SDLLRNPKPW SKLKSGRETF RRMWKWLQEP
360 370 380 390 400
EFQRMSALRL AALVPADPVF QHSGQLPADS LVKIGYPSQS TQSNHMSCKR
410 420 430 440 450
KEQEHGKDRG NTPKKPRLVF TDVQRRTLHA IFKENKRPSK ELQITISQQL
460 470 480 490
GLELSTVSNF FMNARRRSLD KWQDEGNSGS GNTSSSSSTC TKA
Length:493
Mass (Da):54,353
Last modified:May 1, 2007 - v1
Checksum:i0386A9E6ECB83B90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC135775 mRNA. Translation: AAI35776.1.
RefSeqiNP_001093730.1. NM_001100260.1.
UniGeneiStr.28071.

Genome annotation databases

GeneIDi100101763.
KEGGixtr:100101763.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC135775 mRNA. Translation: AAI35776.1.
RefSeqiNP_001093730.1. NM_001100260.1.
UniGeneiStr.28071.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2D5VX-ray2.00A/B282-472[»]
ProteinModelPortaliA4II00.
SMRiA4II00. Positions 284-465.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000013904.

Proteomic databases

PaxDbiA4II00.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100101763.
KEGGixtr:100101763.

Organism-specific databases

CTDi3175.
XenbaseiXB-GENE-480152. onecut1.

Phylogenomic databases

eggNOGiKOG2252. Eukaryota.
ENOG410YWY4. LUCA.
HOVERGENiHBG005981.
KOiK08026.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR003350. CUT_dom.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF02376. CUT. 1 hit.
PF00046. Homeobox. 1 hit.
[Graphical view]
SMARTiSM01109. CUT. 1 hit.
SM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS51042. CUT. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA recognition mechanism of the ONECUT homeodomain of transcription factor HNF-6."
    Iyaguchi D., Yao M., Watanabe N., Nishihira J., Tanaka I.
    Structure 15:75-83(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 282-472.
  2. NIH - Xenopus Gene Collection (XGC) project
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Whole embryoImported.

Entry informationi

Entry nameiA4II00_XENTR
AccessioniPrimary (citable) accession number: A4II00
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: May 11, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.