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A4IGL3 (LAMP5_XENTR) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lysosome-associated membrane glycoprotein 5
Alternative name(s):
Lysosome-associated membrane protein 5
Short name=LAMP-5
Gene names
Name:lamp5
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis) [Reference proteome]
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Cell membrane; Single-pass type I membrane protein By similarity. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein By similarity. Endosome membrane; Single-pass type I membrane protein By similarity. Cytoplasmic vesicle By similarity. Cell projectiondendrite By similarity. Cell projectiongrowth cone membrane By similarity. Early endosome membrane; Single-pass type I membrane protein By similarity. Recycling endosome By similarity.

Post-translational modification

Glycosylated By similarity.

Sequence similarities

Belongs to the LAMP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 Potential
Chain28 – 276249Lysosome-associated membrane glycoprotein 5
PRO_0000360416

Regions

Topological domain28 – 231204Extracellular Potential
Transmembrane232 – 25221Helical; Potential
Topological domain253 – 27624Cytoplasmic Potential

Amino acid modifications

Glycosylation331N-linked (GlcNAc...) Potential
Glycosylation511N-linked (GlcNAc...) Potential
Glycosylation1001N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A4IGL3 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: 8D0D7B4E01A55AE4

FASTA27631,485
        10         20         30         40         50         60 
MDYRACTSAL RMPVLLLLLC TFSCNLAEQE VENLSGLSSN PDKNIFAIRE NGTTCLMAEF 

        70         80         90        100        110        120 
SARILVPYEV PSSNEVDWDL EEASIQLPRD TEIRGKCWNN ESELHLSWLD KAYTLKLFFS 

       130        140        150        160        170        180 
KEGQDASKSR SWKMSKIQFL YDPSEHTIFK SGARPGRHTA NSHHLSLMVT PAGMSYECEA 

       190        200        210        220        230        240 
TQRISLTSTD HQKIVVLYLS EVHLQPFDIK SDFVYSEEYK CPTDQRKQLE ETLPLILGLT 

       250        260        270 
LGVAILIIVA VYHIHHKMTA NQVQIPRDRS LYKHMG 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC135151 mRNA. Translation: AAI35152.1.
RefSeqNP_001090781.1. NM_001097312.1.
UniGeneStr.12939.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSXETT00000033005; ENSXETP00000033005; ENSXETG00000015086.
GeneID100037871.
KEGGxtr:100037871.

Organism-specific databases

CTD24141.
XenbaseXB-GENE-941198. lamp5.

Phylogenomic databases

eggNOGNOG41798.
GeneTreeENSGT00390000012584.
HOGENOMHOG000231912.
HOVERGENHBG051186.
OMACPVDERE.
OrthoDBEOG7DRJ3S.
TreeFamTF330776.

Gene expression databases

BgeeA4IGL3.

Family and domain databases

InterProIPR002000. Lysosome-assoc_membr_glycop.
[Graphical view]
PANTHERPTHR11506. PTHR11506. 1 hit.
PfamPF01299. Lamp. 1 hit.
[Graphical view]
PROSITEPS00310. LAMP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLAMP5_XENTR
AccessionPrimary (citable) accession number: A4IGL3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: May 1, 2007
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families