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A4IGL3

- LAMP5_XENTR

UniProt

A4IGL3 - LAMP5_XENTR

Protein

Lysosome-associated membrane glycoprotein 5

Gene

lamp5

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (01 May 2007)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lysosome-associated membrane glycoprotein 5
    Alternative name(s):
    Lysosome-associated membrane protein 5
    Short name:
    LAMP-5
    Gene namesi
    Name:lamp5
    OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
    Taxonomic identifieri8364 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
    ProteomesiUP000008143: Unplaced

    Organism-specific databases

    XenbaseiXB-GENE-941198. lamp5.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasmic vesicle membrane Source: UniProtKB
    2. dendrite Source: UniProtKB-SubCell
    3. dendrite membrane Source: UniProtKB
    4. early endosome membrane Source: UniProtKB
    5. endoplasmic reticulum-Golgi intermediate compartment membrane Source: UniProtKB
    6. endosome membrane Source: UniProtKB
    7. growth cone membrane Source: UniProtKB
    8. integral component of membrane Source: UniProtKB-KW
    9. plasma membrane Source: UniProtKB
    10. recycling endosome membrane Source: UniProtKB

    Keywords - Cellular componenti

    Cell membrane, Cell projection, Cytoplasmic vesicle, Endosome, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2727Sequence AnalysisAdd
    BLAST
    Chaini28 – 276249Lysosome-associated membrane glycoprotein 5PRO_0000360416Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi33 – 331N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi51 – 511N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi100 – 1001N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    Glycosylated.By similarity

    Keywords - PTMi

    Glycoprotein

    Expressioni

    Gene expression databases

    BgeeiA4IGL3.

    Structurei

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini28 – 231204ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini253 – 27624CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei232 – 25221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LAMP family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG41798.
    GeneTreeiENSGT00390000012584.
    HOGENOMiHOG000231912.
    HOVERGENiHBG051186.
    OMAiCPVDERE.
    OrthoDBiEOG7DRJ3S.
    TreeFamiTF330776.

    Family and domain databases

    InterProiIPR002000. Lysosome-assoc_membr_glycop.
    [Graphical view]
    PANTHERiPTHR11506. PTHR11506. 1 hit.
    PfamiPF01299. Lamp. 1 hit.
    [Graphical view]
    PROSITEiPS00310. LAMP_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    A4IGL3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDYRACTSAL RMPVLLLLLC TFSCNLAEQE VENLSGLSSN PDKNIFAIRE    50
    NGTTCLMAEF SARILVPYEV PSSNEVDWDL EEASIQLPRD TEIRGKCWNN 100
    ESELHLSWLD KAYTLKLFFS KEGQDASKSR SWKMSKIQFL YDPSEHTIFK 150
    SGARPGRHTA NSHHLSLMVT PAGMSYECEA TQRISLTSTD HQKIVVLYLS 200
    EVHLQPFDIK SDFVYSEEYK CPTDQRKQLE ETLPLILGLT LGVAILIIVA 250
    VYHIHHKMTA NQVQIPRDRS LYKHMG 276
    Length:276
    Mass (Da):31,485
    Last modified:May 1, 2007 - v1
    Checksum:i8D0D7B4E01A55AE4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC135151 mRNA. Translation: AAI35152.1.
    RefSeqiNP_001090781.1. NM_001097312.1.
    UniGeneiStr.12939.

    Genome annotation databases

    EnsembliENSXETT00000033005; ENSXETP00000033005; ENSXETG00000015086.
    GeneIDi100037871.
    KEGGixtr:100037871.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC135151 mRNA. Translation: AAI35152.1 .
    RefSeqi NP_001090781.1. NM_001097312.1.
    UniGenei Str.12939.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSXETT00000033005 ; ENSXETP00000033005 ; ENSXETG00000015086 .
    GeneIDi 100037871.
    KEGGi xtr:100037871.

    Organism-specific databases

    CTDi 24141.
    Xenbasei XB-GENE-941198. lamp5.

    Phylogenomic databases

    eggNOGi NOG41798.
    GeneTreei ENSGT00390000012584.
    HOGENOMi HOG000231912.
    HOVERGENi HBG051186.
    OMAi CPVDERE.
    OrthoDBi EOG7DRJ3S.
    TreeFami TF330776.

    Gene expression databases

    Bgeei A4IGL3.

    Family and domain databases

    InterProi IPR002000. Lysosome-assoc_membr_glycop.
    [Graphical view ]
    PANTHERi PTHR11506. PTHR11506. 1 hit.
    Pfami PF01299. Lamp. 1 hit.
    [Graphical view ]
    PROSITEi PS00310. LAMP_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Embryo.

    Entry informationi

    Entry nameiLAMP5_XENTR
    AccessioniPrimary (citable) accession number: A4IGL3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 20, 2009
    Last sequence update: May 1, 2007
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3