DNA ligase - Bos taurus (Bovine)

Contribute

Send feedback

Read comments (?) or add your own

A4IFC8 (A4IFC8_BOVIN) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 54. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

text xml rdf/xml gff fasta

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

Name:

LIG1 EMBL AAI34519.1 Ensembl ENSBTAP00000031866

Organism

Bos taurus (Bovine) [Reference proteome]

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	916 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW double-strand break repair via nonhomologous end joining Inferred from electronic annotation. Source: Compara lagging strand elongation Inferred from Biological aspect of Ancestor. Source: RefGenome response to hydrogen peroxide Inferred from electronic annotation. Source: Compara
Cellular_component	chromosome Inferred from Biological aspect of Ancestor. Source: RefGenome mitochondrion Inferred from Biological aspect of Ancestor. Source: RefGenome nucleus Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

A4IFC8 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: 703226C6B9D7594B
Show »

FASTA

916

101,316

        10         20         30         40         50         60 
MQRSIMSFFQ PKKEGKAKKP EKETAKSIRE TESPPKVALK ERNRVVSEGD SPVKRPGRKA 

        70         80         90        100        110        120 
TRVLGSEGEE EEEEAPTTPR SQKPASDSPQ ASPPSPVTLP ESSPSHSKPS PAVASPSGIP 

       130        140        150        160        170        180 
KRRTARKQLP KRTFQDVLKE QGEDKDPETK KKKEEEAETP IESLPEPEGD DKEEVEGGDQ 

       190        200        210        220        230        240 
PTTPPEPRKT STESLTESVS EPGVTVKQEP QEDGQAQPPP KTPKTLSSFF SPRKPAVKKE 

       250        260        270        280        290        300 
AKEEGPGALR KDEIKGHVDP ASYNPAKNNY HPIEDACWKA GQRVPYLAVA RAFEKIEEVS 

       310        320        330        340        350        360 
ARLRMVETLS NLLRSVVALS PADLLPVLYL SLNRLGPPQQ GLELGIGEGI LLKAVAQATG 

       370        380        390        400        410        420 
RQLESVRAEV AEKGDVGLVA ESSRSTQRLV LPPPALTAAG VFAKFRDIAQ LAGSASTTKK 

       430        440        450        460        470        480 
IDVIKGLFVA CRHSEARFIA RALSGRLRLG LAEQSVLAAL AQAVSLTPPS QECPPAVVDA 

       490        500        510        520        530        540 
GKGKTAEARK TWLEEQGMIL KQTFCEVPDL ERIVPVLLEH GLERLPEHCR LSPGVPLKPM 

       550        560        570        580        590        600 
LAHPTRGVSE VLKRFEEAAF TCEYKYDGQR AQIHVLEGGE VKIFSRNQED NTGRYPDIIS 

       610        620        630        640        650        660 
RIPKIKLPSV TSFILDTEAV AWDREKKQIQ PFQVLTTRKR KEVDAAEIQV QVCLYAFDLI 

       670        680        690        700        710        720 
YLNGKSLVRE PLSRRRQLLR ENFVETEGEF VFATSLDTKD TEQIAEFLEQ SVKDSCEGLM 

       730        740        750        760        770        780 
VKTLDVDATY EIAKRSHNWL KLKKDYLEGV GDTLDLVVIG AYLGKGKRAG RYGGFLLASY 

       790        800        810        820        830        840 
DEESEEFQAI CKLGTGFSDE ELEEHHQRLQ ALVLPTPRSY VRADGAVAPD HWLDPSDVWE 

       850        860        870        880        890        900 
VKCADLSLSP IYPAARGLVD SEKGISLRFP RFIRVREDKK PEQATTSAQV AGLYKKQSQI 

       910 
QNQQGAEPDS EQEEFY

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y., Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C., Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J. Marra M.A. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: L1 Hereford EMBL AAI34519.1. Tissue: Ascending colon EMBL AAI34519.1.
[2]	"A whole-genome assembly of the domestic cow, Bos taurus." Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L. Genome Biol. 10:R42-R42(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hereford Ensembl ENSBTAP00000031866.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Hereford Ensembl ENSBTAP00000031866.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DAAA02047435 Genomic DNA. No translation available. BC134518 mRNA. Translation: AAI34519.1.
IPI	IPI00686777.
RefSeq	NP_001096018.1. NM_001102548.1.
UniGene	Bt.12876.
3D structure databases
SMR	A4IFC8. Positions 259-898.
ModBase	Search...
Protein-protein interaction databases
STRING	9913.ENSBTAP00000019427.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSBTAT00000031920; ENSBTAP00000031866; ENSBTAG00000014595.
GeneID	100124507.
KEGG	bta:100124507.
Organism-specific databases
CTD	3978.
Phylogenomic databases
eggNOG	COG1793.
GeneTree	ENSGT00700000104556.
HOGENOM	HOG000036006.
HOVERGEN	HBG005514.
KO	K10747.
OMA	AQVACLY.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
InterPro	IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20788728.

Entry information

Entry name

A4IFC8_BOVIN

Accession

Primary (citable) accession number: A4IFC8
Secondary accession number(s): F1MSC6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Other

Entry information