Putative 5-methyltetrahydropteroyltriglutamate-homocystein e S-methyltransferase

Preferred order of sections

Names and origin

Protein names

Submitted name:
Putative 5-methyltetrahydropteroyltriglutamate-homocystein e S-methyltransferase EMBL CAM70317.1
EC=2.1.1.14 EMBL CAM70317.1

Gene names

ORF Names:

LINJ_31_0010 EMBL CAM70317.1

Organism

Leishmania infantum

Taxonomic identifier

5671 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania

Protein attributes

Sequence length	770 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

Ontologies

Keywords
Molecular function	Methyltransferase EMBL CAM70317.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	methionine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

A4I695 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: F6E6F41A162EA362
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FASTA

770

85,929

        10         20         30         40         50         60 
MHSLVTTHTL GFPRVGGQRE LKKALESYWR GDLTEAALRQ VGSDLRKRHL QEQNERGVTL 

        70         80         90        100        110        120 
LPVGDFAWYD HVLTTSLMLG NVPPRHRAGA DAAVDLDTLF RVARGRAPTG APAAAAEMTK 

       130        140        150        160        170        180 
WFNTNYHYIV PEFTSASAAF SVSWPQLFEE LEEAKELFNA ERLKAVVLGP VTYVYLGKVK 

       190        200        210        220        230        240 
GEEPFDRASL LPKLVPVYAE ILKRVAALGV TWVQIDEPAL VLELDSSWRS AYQETYRGLR 

       250        260        270        280        290        300 
AAIGTDVKLL LTTYFESVSH HLPLIASLPV NGLHVDLSLQ TQSALDVERA LPEDWVLSAG 

       310        320        330        340        350        360 
VVNGRNVWRS DLLDAYHLLA SLRKQSPRRA LWIGTSCSLL HSPINLECET GLEPVVKEWL 

       370        380        390        400        410        420 
AFAVQKCGEL RLLADAVITE SEAAVAAYTA PLRARQQTEG VVRKEVRERV AGLTAADACR 

       430        440        450        460        470        480 
LDPFPQRWVV QQEKLKLPLW PTTTIGSFPQ TSEVRAQRLA YKKGRVDKET YESQLKVHIA 

       490        500        510        520        530        540 
YALQQQEDIG LDVLVHGEAE RNDMVEYFGE QLEGFAFTQN GWVQSYGSRC VKPPIIVGDI 

       550        560        570        580        590        600 
SRPHPMTVSW AAYAQSLTQR PVKGMLTGPV TILCWSFIRE DLSRQSVTEQ LALAIRDEVC 

       610        620        630        640        650        660 
DLERAGIKVI QVDEPGLREG LPLQRSKWEA YLDWASRSFR VSTSGVAPQT QIHTHMCYAE 

       670        680        690        700        710        720 
VNDVIKTIAS MDADVISIEA SRSDMEPLTS FADFTYPNAV GPGVYDIHSP NIPTTQSIVD 

       730        740        750        760        770 
LLLKATQHLP VRQLWVNPDC GLKTRTWDEC RAALQNMVAA ATELRRTKPQ

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References

[1]

"Comparative genomic analysis of three Leishmania species that cause diverse human disease."
Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A., Fraser A., Rajandream M.-A., Carver T., Norbertczak H., Chillingworth T., Hance Z.

Berriman M.
Nat. Genet. 39:839-847(2007) [PubMed: 17572675] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR796463 Genomic DNA. Translation: CAM70317.1.
RefSeq	XP_001467264.1. XM_001467227.1.
3D structure databases
ProteinModelPortal	A4I695.
ModBase	Search...
Protein-protein interaction databases
STRING	A4I695.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5071705.
KEGG	lif:LINJ_31_0010.
Phylogenomic databases
eggNOG	KOG2263.
HOGENOM	HBG287495.
OMA	NIWANDF.
PhylomeDB	A4I695.
ProtClustDB	CLSZ2430700.
Family and domain databases
HAMAP	MF_00172. Meth_synth. [Tree]
InterPro	IPR013215. Cbl-indep_Met_Synth_N. IPR006276. Cobalamin-indep_Met_synthase. IPR002629. Methionine_synth. [Graphical view]
KO	K00549.
Pfam	PF08267. Meth_synt_1. 1 hit. PF01717. Meth_synt_2. 1 hit. [Graphical view]
PIRSF	PIRSF000382. MeTrfase_B12_ind. 1 hit.
TIGRFAMs	TIGR01371. Met_syn_B12ind. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4I695_LEIIN

Accession

Primary (citable) accession number: A4I695

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Preferred order of sections

Names and origin

Protein attributes

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry information