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A4I634

- A4I634_LEIIN

UniProt

A4I634 - A4I634_LEIIN

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Protein
DNA ligase
Gene
LINJ_30_3490
Organism
Leishmania infantum
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:LINJ_30_3490Imported
OrganismiLeishmania infantum
Taxonomic identifieri5671 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
ProteomesiUP000008153: Chromosome 30

Interactioni

Protein-protein interaction databases

STRINGi5671.LinJ30.3920.

Structurei

3D structure databases

ProteinModelPortaliA4I634.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
KOiK10747.
OMAiLDPSGYN.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4I634-1 [UniParc]FASTAAdd to Basket

« Hide

MAKLFQESSF DPVTTFEAVW LPPRVPVAPP TAGASEPVPF AAVVDVLADI    50
SATGSRLECL KQLTFLLLAV IERCPEDLVP VMYLVINKHA PQHEGVELGI 100
GDAVLVKAVA ECCGMTEARA KEAYRQSGDL AEIAQMHKQK QSTLMKPKPL 150
SARSVFKTYK EIAMMSGRDV MRRRSDLIKG LLRDAQGPEV NLIVRGLQQK 200
MRIGLAEPSA LAAVGYAFAL HFLGGAQMHK MDEVQLQTLL NTGADSLARI 250
FYEVPSLDVV LSAVLANGFM TLVPGSSIAK RYAKDLSIRP GLPVKPQLAY 300
PTSSITVILD RLQGKKFTSE YKYDGERAQI HYDKDKGFHI FSRNSETHTG 350
KYPDVISMLP KVFDPVEVQS FILDSEVVAV HPETGALQAF QVLQHRGRKN 400
IAEEDVSIPV CVFVFDILYF NGEPQLNKTL QQRRELLWRC IHPLPAKLSF 450
ATYLDSDKVE DMQTFLERSI ADGCEGLMVK TLDEEANYTP AKRSHYWLKL 500
KKDYMDGVTD TLDLVPIAAF HGKGKRTGVF GGFLLACYDP KADEYQSICK 550
IGTGFQDEEL EKLTQSLKPF VVDDKPRYYR AGGEEPDVWL TEAQVWEVKA 600
ADLSVSPVHQ AAVGLVDPSK GIALRFPRYL RQREDKKPAD ATNAQQVADM 650
YKAQSLAVQH EANGDAE 667
Length:667
Mass (Da):74,064
Last modified:May 1, 2007 - v1
Checksum:iDAC701EBA6D3049F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FR796462 Genomic DNA. Translation: CAM70256.1.
RefSeqiXP_001467203.1. XM_001467166.1.

Genome annotation databases

GeneIDi5071249.
KEGGilif:LINJ_30_3490.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FR796462 Genomic DNA. Translation: CAM70256.1 .
RefSeqi XP_001467203.1. XM_001467166.1.

3D structure databases

ProteinModelPortali A4I634.
ModBasei Search...

Protein-protein interaction databases

STRINGi 5671.LinJ30.3920.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5071249.
KEGGi lif:LINJ_30_3490.

Phylogenomic databases

eggNOGi COG1793.
KOi K10747.
OMAi LDPSGYN.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JPCM5Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JPCM5Imported.

Entry informationi

Entry nameiA4I634_LEIIN
AccessioniPrimary (citable) accession number: A4I634
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: July 9, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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