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A4I634

- A4I634_LEIIN

UniProt

A4I634 - A4I634_LEIIN

Protein

DNA ligase

Gene

LINJ_30_3490

Organism
Leishmania infantum
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (01 May 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:LINJ_30_3490Imported
    OrganismiLeishmania infantumImported
    Taxonomic identifieri5671 [NCBI]
    Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
    ProteomesiUP000008153: Chromosome 30

    Interactioni

    Protein-protein interaction databases

    STRINGi5671.LinJ30.3920.

    Structurei

    3D structure databases

    ProteinModelPortaliA4I634.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1793.
    KOiK10747.
    OMAiLDPSGYN.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4I634-1 [UniParc]FASTAAdd to Basket

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    MAKLFQESSF DPVTTFEAVW LPPRVPVAPP TAGASEPVPF AAVVDVLADI    50
    SATGSRLECL KQLTFLLLAV IERCPEDLVP VMYLVINKHA PQHEGVELGI 100
    GDAVLVKAVA ECCGMTEARA KEAYRQSGDL AEIAQMHKQK QSTLMKPKPL 150
    SARSVFKTYK EIAMMSGRDV MRRRSDLIKG LLRDAQGPEV NLIVRGLQQK 200
    MRIGLAEPSA LAAVGYAFAL HFLGGAQMHK MDEVQLQTLL NTGADSLARI 250
    FYEVPSLDVV LSAVLANGFM TLVPGSSIAK RYAKDLSIRP GLPVKPQLAY 300
    PTSSITVILD RLQGKKFTSE YKYDGERAQI HYDKDKGFHI FSRNSETHTG 350
    KYPDVISMLP KVFDPVEVQS FILDSEVVAV HPETGALQAF QVLQHRGRKN 400
    IAEEDVSIPV CVFVFDILYF NGEPQLNKTL QQRRELLWRC IHPLPAKLSF 450
    ATYLDSDKVE DMQTFLERSI ADGCEGLMVK TLDEEANYTP AKRSHYWLKL 500
    KKDYMDGVTD TLDLVPIAAF HGKGKRTGVF GGFLLACYDP KADEYQSICK 550
    IGTGFQDEEL EKLTQSLKPF VVDDKPRYYR AGGEEPDVWL TEAQVWEVKA 600
    ADLSVSPVHQ AAVGLVDPSK GIALRFPRYL RQREDKKPAD ATNAQQVADM 650
    YKAQSLAVQH EANGDAE 667
    Length:667
    Mass (Da):74,064
    Last modified:May 1, 2007 - v1
    Checksum:iDAC701EBA6D3049F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FR796462 Genomic DNA. Translation: CAM70256.1.
    RefSeqiXP_001467203.1. XM_001467166.1.

    Genome annotation databases

    GeneIDi5071249.
    KEGGilif:LINJ_30_3490.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FR796462 Genomic DNA. Translation: CAM70256.1 .
    RefSeqi XP_001467203.1. XM_001467166.1.

    3D structure databases

    ProteinModelPortali A4I634.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5671.LinJ30.3920.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5071249.
    KEGGi lif:LINJ_30_3490.

    Phylogenomic databases

    eggNOGi COG1793.
    KOi K10747.
    OMAi LDPSGYN.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JPCM5Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JPCM5Imported.

    Entry informationi

    Entry nameiA4I634_LEIIN
    AccessioniPrimary (citable) accession number: A4I634
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2007
    Last sequence update: May 1, 2007
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3