A4I5Y9 (A4I5Y9_LEIIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative homoserine kinase EMBL CAM70211.1
EC=2.7.1.39 EMBL CAM70211.1

Gene names

ORF Names:

LINJ_30_3120 EMBL CAM70211.1

Organism

Leishmania infantum

Taxonomic identifier

5671 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the GHMP kinase family. RuleBase RU004209

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU003563 Nucleotide-binding
Molecular function	Kinase RuleBase RU003563 EMBL CAM70211.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	threonine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4I5Y9 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: 2C097282DE856F5E	FASTA	341	36,461
	10 20 30 40 50 60 MSDEAATPLP KKVSLRVPAT TANIGPAYDT LGMALSIFME LTVELAETFS MTVTGEGQEY 70 80 90 100 110 120 ISTGEDNMVV QTCRIAFEEY AHKSMPPLKF TMHNNIPYKC GCGSSSAAAV AGFVAGMTLS 130 140 150 160 170 180 GLTMETHNNE SLLSAISKIE GHSDNAASAI YGGIQLVYKK DDDRAMTYHV PTPPNLSIVL 190 200 210 220 230 240 FVPHKLMKAS THVTRDLVPT TVSLRDAVRN ISGTAILTLA LSTGDLRMLT DASDCLHEQQ 250 260 270 280 290 300 RSRKLYPHYS ACAKAAREAG AVYAFLSGAG PSVCAMVPGR HGDLLTQPME ERKAEVVAEA 310 320 330 340 MVKAAEAVGV QGRVIITMPS DFGVHLSGTT CIRPNIQYTS I

References

[1]

"Comparative genomic analysis of three Leishmania species that cause diverse human disease." Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A., Fraser A., Rajandream M.-A., Carver T., Norbertczak H., Chillingworth T., Hance Z. , Jagels K., Moule S., Ormond D., Rutter S., Sqaures R., Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S., Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P., Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.O., Barrell B., Cruz A.K., Mottram J.C., Smith D.F., Berriman M. Nat. Genet. 39:839-847(2007) [PubMed: 17572675] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR796462 Genomic DNA. Translation: CAM70211.1.
RefSeq	XP_001467158.1. XM_001467121.1.
3D structure databases
ProteinModelPortal	A4I5Y9.
ModBase	Search...
Protein-protein interaction databases
STRING	A4I5Y9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5071204.
KEGG	lif:LINJ_30_3120.
Phylogenomic databases
eggNOG	KOG1537.
HOGENOM	HBG646290.
OMA	RSYDPLE.
PhylomeDB	A4I5Y9.
ProtClustDB	PTZ00299.
Family and domain databases
InterPro	IPR006204. GHMP_kinase. IPR013750. GHMP_kinase_C. IPR000870. Homoserine_kinase. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KO	K00872.
Pfam	PF08544. GHMP_kinases_C. 1 hit. PF00288. GHMP_kinases_N. 1 hit. [Graphical view]
PIRSF	PIRSF000676. Homoser_kin. 1 hit.
PRINTS	PR00958. HOMSERKINASE.
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR00191. ThrB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4I5Y9_LEIIN

Accession

Primary (citable) accession number: A4I5Y9

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)