A4I3K7 (A4I3K7_LEIIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative phenylalanine-4-hydroxylase EMBL CAM69361.1
EC=1.14.16.1 EMBL CAM69361.1

Gene names

Name:	PAH EMBL CAM69361.1
ORF Names:	LINJ_28_1390 EMBL CAM69361.1

Organism

Leishmania infantum

Taxonomic identifier

5671 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL CAM69361.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro phenylalanine 4-monooxygenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4I3K7 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: 8C3BFC2758110E12	FASTA	452	51,487
	10 20 30 40 50 60 MLLRSRLLLE AGMAAAATLK DQYASSGSNI KGADKKTRCR TSLQVSLSTD KPGELCHLLS 70 80 90 100 110 120 VFKPYSINIS QVANRPRAYE NKAPLRTIFL DVDAYIEDES MKKVMTELHA KFPNVVVAGS 130 140 150 160 170 180 WVIPWYPTEP KDLDELDQST LAAGEELQED PENPHPGFHD EVYRARRREI VGLAKNYKTG 190 200 210 220 230 240 DQIPIVNYTE EENRVWTVVY DHLTRLYPTH ACQQYNYVFP LLLENGVLSR TQTPQLRDVS 250 260 270 280 290 300 EFLNEATGFT VRPVTGLLTS RDFLNALAFR VFYSTQYIRH AAQPLYTPEP DMVHDIIGHL 310 320 330 340 350 360 PLLSDPDFAN FTQTIGLASL GASDELLDKL AKVYWYSVEF GLCSEGGRRK AYGAGILSSC 370 380 390 400 410 420 GELEYALSDK PECVPWDPTM ASKTPFPITK YQPRYFVAES FSDAQRKLET WLSSQEKPLY 430 440 450 TVYNSYSRRV QSYPKNTWNM LQEQMKRTNF TF

References

[1]

"Comparative genomic analysis of three Leishmania species that cause diverse human disease." Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A., Fraser A., Rajandream M.-A., Carver T., Norbertczak H., Chillingworth T., Hance Z. , Jagels K., Moule S., Ormond D., Rutter S., Sqaures R., Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S., Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P., Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.O., Barrell B., Cruz A.K., Mottram J.C., Smith D.F., Berriman M. Nat. Genet. 39:839-847(2007) [PubMed: 17572675] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR796460 Genomic DNA. Translation: CAM69361.1.
RefSeq	XP_001470169.1. XM_001470132.1.
3D structure databases
ProteinModelPortal	A4I3K7.
SMR	A4I3K7. Positions 123-414.
ModBase	Search...
Protein-protein interaction databases
STRING	A4I3K7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5070354.
KEGG	lif:LINJ_28_1390.
Phylogenomic databases
eggNOG	KOG3820.
HOGENOM	HBG484724.
OMA	PRAYENK.
ProtClustDB	CLSZ2734068.
Family and domain databases
InterPro	IPR001273. ArAA_hydroxylase. IPR018301. ArAA_hydroxylase_Fe/CU_BS. IPR019774. Aromatic-AA_hydroxylase_C. IPR019773. Tyrosine_3-monooxygenase-like. [Graphical view]
Gene3D	G3DSA:1.10.800.10. Aaa_hydroxylase. 1 hit.
KO	K00500.
PANTHER	PTHR11473. Aaa_hydroxylase. 1 hit.
Pfam	PF00351. Biopterin_H. 1 hit. [Graphical view]
PIRSF	PIRSF000336. TH. 1 hit.
PRINTS	PR00372. FYWHYDRXLASE.
SUPFAM	SSF56534. Aaa_hydroxylase. 1 hit.
PROSITE	PS00367. BH4_AAA_HYDROXYL_1. 1 hit. PS51410. BH4_AAA_HYDROXYL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4I3K7_LEIIN

Accession

Primary (citable) accession number: A4I3K7

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)