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A4HYH4

- A4HYH4_LEIIN

UniProt

A4HYH4 - A4HYH4_LEIIN

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Protein
Submitted name: Putative mitogen activated protein kinase 4
Gene
MPK4, LINJ_19_1480
Organism
Leishmania infantum
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. MAP kinase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotations, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative mitogen activated protein kinase 4Imported
Gene namesi
Name:MPK4Imported
ORF Names:LINJ_19_1480Imported
OrganismiLeishmania infantum
Taxonomic identifieri5671 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
ProteomesiUP000008153: Chromosome 19

Interactioni

Protein-protein interaction databases

STRINGi5671.LinJ19.1370.

Structurei

3D structure databases

ProteinModelPortaliA4HYH4.

Family & Domainsi

Sequence similaritiesi

Contains protein kinase domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG0515.
KOiK04371.
OMAiRPQSKET.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4HYH4-1 [UniParc]FASTAAdd to Basket

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MAQLVPLVEL PSGKKIYSVR GQQFEVDRQY DLVKVVGFGA CGTVCSAVAN    50
GSGERVAIKR LSRVFGDLRE GKRILREMEI MTSLKHNNLI RLHHFMRPQS 100
KETFEDIYLV MDLYDTDLNR IIRSRQKLTD EHLQYFMIQA FRGLHYLHSA 150
KVMHRDLKPS NLLVNADCAL AICDFGLARD DQVMSSSDLT QYVVTRWYRP 200
PEVLGMGSNQ YTSAVDVWSL GLIFAELMLG RTLLPGTDYI GQLVMIVNLL 250
GSPSIDDMEF LSSEAKAFIL SQPRRPALSF RDLFPMATEE ATDLLSKLLV 300
FHPARRLTAK QVMEHPYFSK YRDAAEEADA PDPFVWNHSH IETKEQLRED 350
LWRVVEAHSQ SNG 363
Length:363
Mass (Da):41,455
Last modified:May 1, 2007 - v1
Checksum:i6DEA46A7E3C41FE3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FR796451 Genomic DNA. Translation: CAM67358.1.
RefSeqiXP_001465115.1. XM_001465078.1.

Genome annotation databases

GeneIDi5068526.
KEGGilif:LINJ_19_1480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FR796451 Genomic DNA. Translation: CAM67358.1 .
RefSeqi XP_001465115.1. XM_001465078.1.

3D structure databases

ProteinModelPortali A4HYH4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5671.LinJ19.1370.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5068526.
KEGGi lif:LINJ_19_1480.

Phylogenomic databases

eggNOGi COG0515.
KOi K04371.
OMAi RPQSKET.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JPCM5Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JPCM5Imported.

Entry informationi

Entry nameiA4HYH4_LEIIN
AccessioniPrimary (citable) accession number: A4HYH4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: July 9, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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