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Protein

Mitogen-activated protein kinase

Gene

MPK4

Organism
Leishmania infantum
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseSAAS annotation (EC:2.7.11.24SAAS annotation)
Gene namesi
Name:MPK4Imported
ORF Names:LINJ_19_1480Imported
OrganismiLeishmania infantumImported
Taxonomic identifieri5671 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
Proteomesi
  • UP000008153 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiTriTrypDB:LinJ.19.1480

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi435258.XP_001465115.1

Structurei

3D structure databases

ProteinModelPortaliA4HYH4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0660 Eukaryota
ENOG410XNY0 LUCA
InParanoidiA4HYH4
KOiK04371
OMAiMEKCLTF

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR003527 MAP_kinase_CS
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS01351 MAPK, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

A4HYH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQLVPLVEL PSGKKIYSVR GQQFEVDRQY DLVKVVGFGA CGTVCSAVAN
60 70 80 90 100
GSGERVAIKR LSRVFGDLRE GKRILREMEI MTSLKHNNLI RLHHFMRPQS
110 120 130 140 150
KETFEDIYLV MDLYDTDLNR IIRSRQKLTD EHLQYFMIQA FRGLHYLHSA
160 170 180 190 200
KVMHRDLKPS NLLVNADCAL AICDFGLARD DQVMSSSDLT QYVVTRWYRP
210 220 230 240 250
PEVLGMGSNQ YTSAVDVWSL GLIFAELMLG RTLLPGTDYI GQLVMIVNLL
260 270 280 290 300
GSPSIDDMEF LSSEAKAFIL SQPRRPALSF RDLFPMATEE ATDLLSKLLV
310 320 330 340 350
FHPARRLTAK QVMEHPYFSK YRDAAEEADA PDPFVWNHSH IETKEQLRED
360
LWRVVEAHSQ SNG
Length:363
Mass (Da):41,455
Last modified:May 1, 2007 - v1
Checksum:i6DEA46A7E3C41FE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796451 Genomic DNA Translation: CAM67358.1
RefSeqiXP_001465115.1, XM_001465078.1

Genome annotation databases

EnsemblProtistsiCAM67358; CAM67358; LINJ_19_1480
GeneDBiLinJ.19.1480:pep
GeneIDi5068526
KEGGilif:LINJ_19_1480

Similar proteinsi

Entry informationi

Entry nameiA4HYH4_LEIIN
AccessioniPrimary (citable) accession number: A4HYH4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: April 25, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health