A4HXM4 (A4HXM4_LEIIN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ferrochelatase-like protein EMBL CAM59843.1
EC=4.99.1.1 EMBL CAM59843.1

Gene names

ORF Names:

LINJ_17_1580 EMBL CAM59843.1

Organism

Leishmania infantum

Taxonomic identifier

5671 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the ferrochelatase family. RuleBase RU004185

Ontologies

Keywords
Molecular function	Lyase EMBL CAM59843.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	heme biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ferrochelatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4HXM4 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: 531482644879B1C4	FASTA	385	42,239
	10 20 30 40 50 60 MSCAPGPTKA VLLVNLGTTT APTAPAVRRF LREFLSDRRV IDVPRFLWHS VLYGFILPFR 70 80 90 100 110 120 PRSITPLYKA IWIKSDSGVV INGKTEGSPL TLYSESLAAK VQASVEKTSG GAVVARHAMR 130 140 150 160 170 180 YGVKNIPSTL KALHDEFATL RELVVLPLFP QYTSTTSASI YDEVFKFYTD TRRRSIPSLR 190 200 210 220 230 240 TIRDYAEHPV YVEALGSSLL SSIKAHVTAK AGAAKDWKSA LSDQLPEIGI IITYHSIPVR 250 260 270 280 290 300 YVEEHDDYPQ RCEATTAAIK AYIEAESGVS LSGCLVHVYQ SQFGNQPWLG PTLNAAATAF 310 320 330 340 350 360 PLPPHDPRKH AFSDAHRNTA LLTKQANVCF AMAPGFAVDC VETLNEIERE AGEVFKQSGG 370 380 REFIYVPCLN DSDTHVKVLT SVVGA

References

[1]

"Comparative genomic analysis of three Leishmania species that cause diverse human disease." Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A., Fraser A., Rajandream M.-A., Carver T., Norbertczak H., Chillingworth T., Hance Z. , Jagels K., Moule S., Ormond D., Rutter S., Sqaures R., Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S., Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P., Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.O., Barrell B., Cruz A.K., Mottram J.C., Smith D.F., Berriman M. Nat. Genet. 39:839-847(2007) [PubMed: 17572675] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR796449 Genomic DNA. Translation: CAM59843.1.
RefSeq	XP_001464815.1. XM_001464778.1.
3D structure databases
ProteinModelPortal	A4HXM4.
ModBase	Search...
Protein-protein interaction databases
STRING	A4HXM4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5068219.
KEGG	lif:LINJ_17_1580.
Phylogenomic databases
HOGENOM	HBG697135.
OMA	TIEEIGM.
PhylomeDB	A4HXM4.
ProtClustDB	CLSZ2456097.
Family and domain databases
HAMAP	MF_00323. Ferrochelatase. [Tree]
InterPro	IPR001015. Ferrochelatase. [Graphical view]
KO	K01772.
PANTHER	PTHR11108. Ferrochelatase. 1 hit.
Pfam	PF00762. Ferrochelatase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00109. HemH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4HXM4_LEIIN

Accession

Primary (citable) accession number: A4HXM4

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)