A4HMX5 (A4HMX5_LEIBR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative glycerol kinase, glycosomal EMBL CAM43516.1
EC=2.7.1.30 EMBL CAM43516.1

Gene names

ORF Names:

LBRM_34_2990 EMBL CAM43516.1

Organism

Leishmania braziliensis

Taxonomic identifier

5660 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania › Leishmania braziliensis species complex

Protein attributes

Sequence length	512 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the FGGY kinase family. RuleBase RU003733

Ontologies

Keywords
Molecular function	Kinase RuleBase RU003733 EMBL CAM43516.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycerol-3-phosphate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	glycerol kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4HMX5 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: E5B461877ACC21F9	FASTA	512	56,235
	10 20 30 40 50 60 MPYVASIDQG TTSSRCIIFD EKFSILSEHQ LAHEQITPQP GWLEHDPEEI YRNCCLCLAE 70 80 90 100 110 120 AVKKLRAKDP KFDKVSAIGI TNQRETGVAW DRQTGKPLCN AIVWSDARTY EVSNRIAKDF 130 140 150 160 170 180 GGGDHNFAAH ITGLPVSTYF TAFKFRWMLE NVPAVAAARK SNMLLLGTIE SWLLWKLSEG 190 200 210 220 230 240 KVFVTDVSNA SRTFLMNLST QQWCDELCEK LDIPRTALPA IRSNSERYCD VTANDYGIRD 250 260 270 280 290 300 ALGVPTPVAG CIGDQQSALF GHMGLHKGDA KNTYGTGCFM LMNVGTEPQF SKNGLLGTIA 310 320 330 340 350 360 YKLGTESAKF ALEGSIAGAG ATMEWMRSNL NFYSHPREID NIARQVSGTD GVVFVPAFGG 370 380 390 400 410 420 LLAPYWDPTA RGTLLGMTYK TNKSHIIRAA LEAISMQVNA VLLAMKEDSG VEIKCLRVDG 430 440 450 460 470 480 GLTRSRLLME MQADILGVDL YVPRLTETTA LGAALCAGLA VGVWKSVKEI QKTAKEQLSG 490 500 510 ETVSPTMTDK QVRKARLEAW NAAVKRSKWA KL

References

[1]

"Comparative genomic analysis of three Leishmania species that cause diverse human disease." Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A., Fraser A., Rajandream M.-A., Carver T., Norbertczak H., Chillingworth T., Hance Z. , Jagels K., Moule S., Ormond D., Rutter S., Sqaures R., Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S., Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P., Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.O., Barrell B., Cruz A.K., Mottram J.C., Smith D.F., Berriman M. Nat. Genet. 39:839-847(2007) [PubMed: 17572675] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MHOM/BR/75/M2904.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR799009 Genomic DNA. Translation: CAM43516.1.
RefSeq	XP_001568405.1. XM_001568355.1.
3D structure databases
ProteinModelPortal	A4HMX5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5419359.
KEGG	lbz:LbrM34_V2.2990.
Organism-specific databases
EuPathDB	EupathDB:LbrM.34.2990.
Phylogenomic databases
HOGENOM	HBG511469.
PhylomeDB	A4HMX5.
ProtClustDB	PTZ00294.
Family and domain databases
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018483. Carb_kinase_FGGY_CS. IPR018484. Carb_kinase_FGGY_N. IPR005999. Glycerol_kin. [Graphical view]
KO	K00864.
PANTHER	PTHR10196. FGGY_kin. 1 hit. PTHR10196:SF9. Glycerol_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01311. Glycerol_kin. 1 hit.
PROSITE	PS00933. FGGY_KINASES_1. 1 hit. PS00445. FGGY_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4HMX5_LEIBR

Accession

Primary (citable) accession number: A4HMX5

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	November 16, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)