A4HGH5 (A4HGH5_LEIBR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative phenylalanine-4-hydroxylase EMBL CAM39668.1
EC=1.14.16.1 EMBL CAM39668.1

Gene names

Name:	PAH EMBL CAM39668.1
ORF Names:	LBRM_28_1380 EMBL CAM39668.1

Organism

Leishmania braziliensis

Taxonomic identifier

5660 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania › Leishmania braziliensis species complex

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL CAM39668.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro phenylalanine 4-monooxygenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4HGH5 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: F336BF2C40EC82BD	FASTA	452	51,498
	10 20 30 40 50 60 MLLRRRLLQQ VGMAASATLK DQYASSGSSI KDADKKTRSR TSLQVSLSTD KSGELCRLLS 70 80 90 100 110 120 VFKPHNINIS QVANRPRAYE NKAPLRTIFL DVEAYIEDQN MKKVMAELRE TFPNVVVAGS 130 140 150 160 170 180 WVIPWYPTEP KDLDELDQST LAAGEELQED PENPHPGFHD EVYRARRREI VGLAKNYKTG 190 200 210 220 230 240 DKIPIVNYTE EENRVWSVVY DHLTRLYPTH ACQQYNYVFP LLLESGVLSR TQMPQLRDVS 250 260 270 280 290 300 DFLNEATGFT VRPVTGLLTS RDFLNALAFR VFYSTQYIRH AAQPLYTPEP DMVHDIIGHL 310 320 330 340 350 360 PLLSDPDFAK FTQTIGLASL GASDELLGKL AKVYWYSVEF GLCSEGGRCK AYGAGILSSS 370 380 390 400 410 420 GELEYALSDK PERVPWDPTV ASITPFPITK YQPRYFVAES FPDAQHKLEA WLSSQEKPLY 430 440 450 TVYNSYSRCV QSYPKNTWHM LQEQMKRTNF TF

References

[1]

"Comparative genomic analysis of three Leishmania species that cause diverse human disease." Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A., Fraser A., Rajandream M.-A., Carver T., Norbertczak H., Chillingworth T., Hance Z. , Jagels K., Moule S., Ormond D., Rutter S., Sqaures R., Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S., Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P., Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.O., Barrell B., Cruz A.K., Mottram J.C., Smith D.F., Berriman M. Nat. Genet. 39:839-847(2007) [PubMed: 17572675] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MHOM/BR/75/M2904.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR799003 Genomic DNA. Translation: CAM39668.1.
RefSeq	XP_001566169.1. XM_001566119.1.
3D structure databases
ProteinModelPortal	A4HGH5.
SMR	A4HGH5. Positions 123-431.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5417044.
KEGG	lbz:LbrM28_V2.1380.
Organism-specific databases
EuPathDB	EupathDB:LbrM.28.1380.
Phylogenomic databases
HOGENOM	HBG484724.
OMA	PRAYENK.
ProtClustDB	CLSZ2734068.
Family and domain databases
InterPro	IPR001273. ArAA_hydroxylase. IPR018301. ArAA_hydroxylase_Fe/CU_BS. IPR019774. Aromatic-AA_hydroxylase_C. [Graphical view]
Gene3D	G3DSA:1.10.800.10. Aaa_hydroxylase. 1 hit.
KO	K00500.
PANTHER	PTHR11473. Aaa_hydroxylase. 1 hit.
Pfam	PF00351. Biopterin_H. 1 hit. [Graphical view]
PRINTS	PR00372. FYWHYDRXLASE.
SUPFAM	SSF56534. Aaa_hydroxylase. 1 hit.
PROSITE	PS00367. BH4_AAA_HYDROXYL_1. 1 hit. PS51410. BH4_AAA_HYDROXYL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4HGH5_LEIBR

Accession

Primary (citable) accession number: A4HGH5

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	November 16, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)