A4HEH1 (A4HEH1_LEIBR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Pyruvate dehydrogenase E1 beta subunit, putative EMBL CAM39227.1
EC=1.2.4.1 EMBL CAM39227.1

Gene names

ORF Names:

LbrM_25_2280 EMBL CAM39227.1

Organism

Leishmania braziliensis

Taxonomic identifier

5660 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmania › Leishmania braziliensis species complex

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL CAM39227.1

Ontologies

Keywords
Ligand	Pyruvate EMBL CAM39227.1
Molecular function	Oxidoreductase EMBL CAM39227.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	pyruvate dehydrogenase (acetyl-transferring) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4HEH1 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: E29C2AE98957EB6B	FASTA	335	36,293
	10 20 30 40 50 60 MATRCATTSM TVRDAIQSAL DEELARDDKV FVIGEEVAQY QGAYKVTKGL SDKYGKDRII 70 80 90 100 110 120 DMPITEHGFT GMAVGAALGG MRPVCEFMTF NFAMQAIDQI VNSAAKSLYM SGGQMKCPIV 130 140 150 160 170 180 FRGPNGASAG VGAQHSQCFG PWYASVPGLK VIAPYNCEDA RGMIKAAIRD DNAVVVLEHE 190 200 210 220 230 240 LLYGESFPVT DVAADKNFVI PFGKAKIERE GKDITLIGFS RGVELCLKTA EKLAAEGVQA 250 260 270 280 290 300 EVINLRSLRP LDRETIFKSI KKTHRAVTVD ESFPVCNIGA EICACVMESD TFDYLDAPIE 310 320 330 RVSCADCPTP YSKEIEMASQ PQVADVMAAA KRVLS

References

[1]

"Comparative genomic analysis of three Leishmania species that cause diverse human disease." Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A., Fraser A., Rajandream M.-A., Carver T., Norbertczak H., Chillingworth T., Hance Z. , Jagels K., Moule S., Ormond D., Rutter S., Sqaures R., Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S., Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P., Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.O., Barrell B., Cruz A.K., Mottram J.C., Smith D.F., Berriman M. Nat. Genet. 39:839-847(2007) [PubMed: 17572675] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MHOM/BR/75/M2904.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CADA01000033 Genomic DNA. Translation: CAM39227.1.
RefSeq	XP_001565729.1. XM_001565679.1.
3D structure databases
ProteinModelPortal	A4HEH1.
SMR	A4HEH1. Positions 7-335.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5416317.
KEGG	lbz:LbrM25_V2.2280.
Organism-specific databases
EuPathDB	EupathDB:LbrM.25.2280.
Phylogenomic databases
HOGENOM	HBG753264.
OMA	MEHAFDY.
PhylomeDB	A4HEH1.
ProtClustDB	PTZ00182.
Family and domain databases
InterPro	IPR009014. Transketo_C/Pyr-ferredox_oxred. IPR015941. Transketolase-like_C. IPR005475. Transketolase-like_Pyr-bd. IPR005476. Transketolase_C. [Graphical view]
Gene3D	G3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KO	K00162.
Pfam	PF02779. Transket_pyr. 1 hit. PF02780. Transketolase_C. 1 hit. [Graphical view]
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
SUPFAM	SSF52922. Transketo_C_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4HEH1_LEIBR

Accession

Primary (citable) accession number: A4HEH1

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	November 16, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)