Receptor-type adenylate cyclase a - Leishmania braziliensis

Preferred order of sections

Names and origin

Protein names

Submitted name:
Receptor-type adenylate cyclase a EMBL CAM37814.1
EC=4.6.1.1 EMBL CAM37814.1

Gene names

ORF Names:

LBRM_17_0010 EMBL CAM37814.1

Organism

Leishmania braziliensis [Reference proteome]

Taxonomic identifier

5660 [NCBI]

Taxonomic lineage

Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmaniinae › Leishmania › Leishmania braziliensis species complex

Protein attributes

Sequence length	1308 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL CAM37814.1 Receptor EMBL CAM37814.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cAMP biosynthetic process Inferred from electronic annotation. Source: GOC intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Molecular_function	adenylate cyclase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

A4H8U6 [UniParc].

Last modified May 1, 2007. Version 1.
Checksum: AE618C828D5018FF
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FASTA

1,308

141,701

        10         20         30         40         50         60 
MYIRPLHSGC RRCGGAGDHA ARLASQWRTA ALLVTAAFTS VLFFSPSWVQ AGITNAADLE 

        70         80         90        100        110        120 
PVYLLNTMYA TDAFVEDDAK ALWKGMDMAF YNSGYKAAGG RPIKILHPDP VQDSLNDTEA 

       130        140        150        160        170        180 
VILHALHRQE KLLAVLGPYM DTCLTVALNS VDVVKSELML LGPFTGSSTV RTWSDSVYFT 

       190        200        210        220        230        240 
RAEPMIELKV VMMHVINTIR ARRVAFMHLT GAHFGEEELL YMQLTLASLL RDPAAVYAAP 

       250        260        270        280        290        300 
LSAINAEVDQ NAFDAMADTH PQVIIVWTAP GKQVARFLEK ALTDSRTSSA YIISCSMMQR 

       310        320        330        340        350        360 
LMFHLHKRLL NSGSIVSRDG QILVSATESP VSDQISKYIK VFKTQMRNYI ENSGSFDYSP 

       370        380        390        400        410        420 
DDETVETLAP TLMSAMPRTR NFTVETFLEA HPDLAQLMVL GWVSGTLVQQ TLERPDWIVS 

       430        440        450        460        470        480 
RSAYKAGLFN QNRFMIGGDY VLGDYGGSCE PLAQYLGATC YCNQGGRAAI LTVLKDASWD 

       490        500        510        520        530        540 
ILPDSLFTYP QSACNSSKAE VIKAATVLIL MHLDSPKLME AGVQMTAIAP DAVQDDSCKR 

       550        560        570        580        590        600 
HSVNRLSLSM TMAAAQRLFD AEVGNYSVDI VAGPMRRTLD VGNTFVVSPL YTRPHLLTKK 

       610        620        630        640        650        660 
RNYVYLMPTL EQQMFLLYFK IDAVRAAVSA GTDTRVTLRG YSADEADTIS DLFCKTAGTF 

       670        680        690        700        710        720 
NLPDPFIIRV PLTESLTGIV SPKGINVVVG MTDGDGSRMA TFLAANPAAI IVVCFDDLAM 

       730        740        750        760        770        780 
HYTELIAALS IQPSSVQSRL ISFNSLPLWS DTSPAAEADS PVLKLFHRRF PDPSNHTPSL 

       790        800        810        820        830        840 
LRDLVTASFI GELIAKVSVP HTQLLAGELY MRSTFTTHNM VFGPFEWGCT TTASGDDCIY 

       850        860        870        880        890        900 
ENYGAQSIAM LSVQRMLDPR VPQLTAPMTP SLVYRPRVAS SALTPAERNG IIAGVVLLVV 

       910        920        930        940        950        960 
ASIAAVGLLL YCCMDNRDND AAPKDGDEPV TLVFTDIESS TALWAVLPQL MADAIVAHHR 

       970        980        990       1000       1010       1020 
VIRQLIAKHG CYEVKTIGDS FMIACKSAHS AVRLACEIQT KLLGHDWGTV SIDAAYREFE 

      1030       1040       1050       1060       1070       1080 
LARADADDDY VPPTARLSEE EYAAVWCGLR VRVGVHTGLC DIRYDEVTKG YDYYGDAPNM 

      1090       1100       1110       1120       1130       1140 
AARTEAVANG GQVVATETAW WALSNEERAG AAHTAMGRQG LRGVPFAVEM FQMDAVPGRR 

      1150       1160       1170       1180       1190       1200 
HAALRTEIEA ILPDETATET ASSAAGALLS SVGTMSGPAA GIALVLTSCF APYPVAQRVR 

      1210       1220       1230       1240       1250       1260 
ELQPLLSKWG VGAPPRSRAV SEEDYCQGLM NRLALRIATV SQARQRMGNG GAVVAGDMPD 

      1270       1280       1290       1300 
VGAGGALNPL VGVGGCGVGG AAPRPSGMTA PPRSGVPSAV RDLRMLRT

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References

[1]

"Comparative genomic analysis of three Leishmania species that cause diverse human disease."
Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A., Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T., Hance Z.

Berriman M.
Nat. Genet. 39:839-847(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MHOM/BR/75/M2904 EMBL CAM37814.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR798991 Genomic DNA. Translation: CAM37814.1.
RefSeq	XP_001562171.1. XM_001562121.1.
3D structure databases
ProteinModelPortal	A4H8U6.
SMR	A4H8U6. Positions 918-1149.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5414461.
KEGG	lbz:LBRM_17_0010.
Phylogenomic databases
KO	K01768.
OMA	VINTIRA.
ProtClustDB	CLSZ2456037.
Family and domain databases
Gene3D	3.30.70.1230. 1 hit.
InterPro	IPR001054. A/G_cyclase. [Graphical view]
Pfam	PF00211. Guanylate_cyc. 1 hit. [Graphical view]
SMART	SM00044. CYCc. 1 hit. [Graphical view]
SUPFAM	SSF55073. A/G_cyclase. 1 hit.
PROSITE	PS50125. GUANYLATE_CYCLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4H8U6_LEIBR

Accession

Primary (citable) accession number: A4H8U6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	May 29, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Preferred order of sections

Names and origin

Protein attributes

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry information