A4H8B1 (A4H8B1_LEIBR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative glutaminyl-tRNA synthetase EMBL CAM42160.1
EC=6.1.1.18 EMBL CAM42160.1

Gene names

ORF Names:

LBRM_15_1430 EMBL CAM42160.1

Organism

Leishmania braziliensis [Reference proteome]

Taxonomic identifier

5660 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Leishmaniinae › Leishmania › Viannia › Leishmania braziliensis species complex

Protein attributes

Sequence length	616 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489

Ontologies

Keywords
Biological process	Protein biosynthesis RuleBase RU003489
Ligand	ATP-binding RuleBase RU003489 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase RuleBase RU003489 EMBL CAM42160.1 Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glutaminyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glutamine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4H8B1 [UniParc]. Last modified May 1, 2007. Version 1. Checksum: 64435099E17E8069	FASTA	616	71,033
	10 20 30 40 50 60 MHGAESSAAP RLWLLKHTHP STRSYRTYYP FKTLTKTTFR RFLPRLAKMA APAAAEVEVE 70 80 90 100 110 120 TKRDLSVLQS GRPVPGCRNT PELLAAHDAV TGGKPYFRFP PEPNGFLHIG HAKSMNLNFG 130 140 150 160 170 180 SARAHGGKCY LRYDDTNPEA EEQIYIDAIM EMVEWMGWKP DWVTFSSDYF DQLHAFAVQL 190 200 210 220 230 240 IKKGKAYVDH STPDELKQQR EQREDSPWRN RSVEENLLLF NRMRQGRYAE GEATLRVKAD 250 260 270 280 290 300 MKSDNPNMRD FIAYRVKYVE HPHIHDKWCI YPSYDFTHCL IDSLEDIDYS LCTLEFETRR 310 320 330 340 350 360 ESYFWLLSEL NLWRPHVWEF SRLNVTGSLL SKRKINVLVR GGIVRGFDDP RLLTLAGMRR 370 380 390 400 410 420 RGYTPAAINR FCELVGITRS MNVIQLSMLE NTLREDLDEH CERRLMVIDP IKVVVDNWKG 430 440 450 460 470 480 ERTFECPNHP RKPELGNRTM SFTDTFYVDR SDFHTEDNNK KFYGLAPGPR VVGLKYSGNV 490 500 510 520 530 540 VCNGFEVDAE GRPTVIHVDI DFERKDKPKT NISWVSATAC TPVEVRLYTA LLRDDCAAID 550 560 570 580 590 600 PDFLKFIDEK SEVVSHGYAE EGIKGLKHFE SIQVERFGYF VVDPDTTADH LVMNRVLGLR 610 EDKDKATVAE PAPAKK

References

[1]

"Comparative genomic analysis of three Leishmania species that cause diverse human disease." Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A., Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A., Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T., Hance Z. , Jagels K., Moule S., Ormond D., Rutter S., Squares R., Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S., Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P., Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K., Mottram J.C., Smith D.F., Berriman M. Nat. Genet. 39:839-847(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MHOM/BR/75/M2904 EMBL CAM42160.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FR798989 Genomic DNA. Translation: CAM42160.1.
RefSeq	XP_001563590.1. XM_001563540.1.
3D structure databases
ProteinModelPortal	A4H8B1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5414109.
KEGG	lbz:LBRM_15_1430.
Phylogenomic databases
KO	K01886.
OMA	KEVCRFQ.
ProtClustDB	PTZ00437.
Family and domain databases
Gene3D	1.10.1160.10. 1 hit. 2.40.240.10. 2 hits. 3.40.50.620. 2 hits.
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR004514. Gln-tRNA-synth_Ib. IPR000924. Glu/Gln-tRNA-synth_Ib. IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl. IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom. IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd. IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl. IPR011035. Ribosomal_L25/Gln-tRNA_synth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
PANTHER	PTHR10119. PTHR10119. 1 hit.
Pfam	PF00749. tRNA-synt_1c. 1 hit. PF03950. tRNA-synt_1c_C. 1 hit. [Graphical view]
PRINTS	PR00987. TRNASYNTHGLU.
SUPFAM	SSF50715. Ribosomal_L25rel. 1 hit.
TIGRFAMs	TIGR00440. glnS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4H8B1_LEIBR

Accession

Primary (citable) accession number: A4H8B1

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	May 29, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)