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Protein

Superoxide dismutase

Gene

FESODA

Organism
Leishmania braziliensis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:FESODAImported
ORF Names:LBRM_08_0330Imported
OrganismiLeishmania braziliensisImported
Taxonomic identifieri5660 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmaniaLeishmania braziliensis species complex
ProteomesiUP000007258 Componenti: Chromosome 8

Interactioni

Protein-protein interaction databases

STRINGi420245.XP_001562094.1.

Structurei

3D structure databases

ProteinModelPortaliA4H599.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

InParanoidiA4H599.
KOiK04564.
OMAiWEHAYYK.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4H599-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRRVSIKTV MATAAVHASF LSYHSLPELQ YPAELPKLEY SYADGIKPVF
60 70 80 90 100
SARQVELHYT KHHKAYVDKL NTLGTGYEGK PIEEIIKTTN GIAANTVLFN
110 120 130 140 150
QASQHFNHTF FWKCLAPGGK AMPKPLEAAI AKQFGSVDDF KSSFQQAGMN
160 170 180 190 200
NFGSGWTWLC VNPKTRELLI DNTSNAGCPV TAGMRPIFTA DVWEHAYYKD
210 220 230
FENRRADYLK EIWQVVNWEY VAQMYSRAIK
Length:230
Mass (Da):26,110
Last modified:May 1, 2007 - v1
Checksum:iB8F37A55F6004A98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR798982 Genomic DNA. Translation: CAM37121.1.
RefSeqiXP_001562094.1. XM_001562044.2.

Genome annotation databases

GeneIDi5413072.
KEGGilbz:LBRM_08_0330.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR798982 Genomic DNA. Translation: CAM37121.1.
RefSeqiXP_001562094.1. XM_001562044.2.

3D structure databases

ProteinModelPortaliA4H599.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi420245.XP_001562094.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5413072.
KEGGilbz:LBRM_08_0330.

Phylogenomic databases

InParanoidiA4H599.
KOiK04564.
OMAiWEHAYYK.

Family and domain databases

InterProiIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERiPTHR11404. PTHR11404. 1 hit.
PfamiPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MHOM/BR/75/M2904Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MHOM/BR/75/M2904Imported.

Entry informationi

Entry nameiA4H599_LEIBR
AccessioniPrimary (citable) accession number: A4H599
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: July 22, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.