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A4GYX1 (NU1C_POPTR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic

EC=1.6.5.-
Alternative name(s):
NAD(P)H dehydrogenase subunit 1
Short name=NDH subunit 1
NADH-plastoquinone oxidoreductase subunit 1
Gene names
Name:ndhA
Ordered Locus Names:Poptr_cp084
Encoded onPlastid; Chloroplast
OrganismPopulus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa) [Reference proteome]
Taxonomic identifier3694 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesSalicaceaeSaliceaePopulus

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient By similarity. HAMAP-Rule MF_01350

Catalytic activity

NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP-Rule MF_01350

Subunit structure

NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus By similarity.

Subcellular location

Plastidchloroplast thylakoid membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01350.

Sequence similarities

Belongs to the complex I subunit 1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 365365NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic HAMAP-Rule MF_01350
PRO_0000298880

Regions

Transmembrane30 – 5021Helical; Potential
Transmembrane104 – 12421Helical; Potential
Transmembrane129 – 14921Helical; Potential
Transmembrane253 – 27321Helical; Potential
Transmembrane302 – 32221Helical; Potential
Transmembrane338 – 35821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A4GYX1 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: DE2B0A12B481DE59

FASTA36540,394
        10         20         30         40         50         60 
MIIDTTTVQA INSFSRLKSL NEVYGIIWML VPILTLVLGI TIGILVIVWL EREISAGIQQ 

        70         80         90        100        110        120 
RIGPEYAGPF GVLQALADGT KLLFKENLFP SRGDTRLFSI GPSIAVISTL LSYSVIPFGY 

       130        140        150        160        170        180 
HFVLADLNIG VFLWIAISSI APIGLLMSGY GSNNKYSFLG GLRAAAQSIS YEIPLTLCVL 

       190        200        210        220        230        240 
SISLLSNSSS TVDIVEAQSK YGLGGWNLWR QPIGFIIFFI SSLAECERLP FDLPEAEEEL 

       250        260        270        280        290        300 
VAGYQTEYSG IKFGLFYVAS YLNLLVSSLF VAVLYLGGWN ISIPYISVPE FFDFEINKVG 

       310        320        330        340        350        360 
RVFGTTMGIL ITLVKTYLFL FIPITTRWTL PRLRMDQLLN LGWKFLLPIS LGNLLLTTSS 


QLFSL 

« Hide

References

[1]"The genome of black cottonwood, Populus trichocarpa (Torr. & Gray)."
Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I., Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J., Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W., Brun A. expand/collapse author list , Brunner A., Busov V., Campbell M., Carlson J., Chalot M., Chapman J., Chen G.-L., Cooper D., Coutinho P.M., Couturier J., Covert S., Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A., dePamphilis C.W., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J., Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A., Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B., Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S., Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjaervi J., Karlsson J., Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F., Leebens-Mack J., Leple J.-C., Locascio P., Lou Y., Lucas S., Martin F., Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O., Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J., Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J., Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A., Tsai C.-J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S., Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y., Rokhsar D.S.
Science 313:1596-1604(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nisqually.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EF489041 Genomic DNA. Translation: ABO36766.1.
RefSeqYP_001109562.1. NC_009143.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3694.estExt_Genewise1_v1.C_130550001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4929745.
KEGGpop:Poptr_cp084.

Phylogenomic databases

eggNOGCOG1005.
KOK05572.
ProtClustDBCHL00032.

Family and domain databases

HAMAPMF_01350. NDH1_NuoH.
InterProIPR001694. NADH_UbQ_OxRdtase_su1/FPO.
IPR018086. NADH_UbQ_OxRdtase_su1_CS.
[Graphical view]
PANTHERPTHR11432. PTHR11432. 1 hit.
PfamPF00146. NADHdh. 1 hit.
[Graphical view]
PROSITEPS00667. COMPLEX1_ND1_1. 1 hit.
PS00668. COMPLEX1_ND1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNU1C_POPTR
AccessionPrimary (citable) accession number: A4GYX1
Entry history
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: April 17, 2007
Last modified: February 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families