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Protein

DNA-directed RNA polymerase subunit

Gene

J4R

Organism
Vaccinia virus
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotationImported, Transferase
Biological processTranscription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunitUniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:J4RImported
Synonyms:VACV_BRZ_SERRO2_094Imported
ORF Names:List092Imported, LIVPclone14_104Imported, m8114RImported, mO114RImported, VAC_DPP10_107Imported, VAC_DPP11_107Imported, VAC_DPP12_107Imported, VAC_DPP13_107Imported, VAC_DPP15_107Imported, VAC_DPP16_107Imported, VAC_DPP17_107Imported, VAC_DPP19_107Imported, VAC_DPP20_107Imported, VAC_DPP21_107Imported, VAC_DPP25_107Imported, VAC_DPP9_107Imported, VAC_IHDW1_098Imported, VAC_TKT3_086Imported, VAC_TKT4_086Imported, VAC_TP3_101Imported, VAC_TP5_101Imported, VACAC2_107Imported, VACCL3_107Imported, VACV-DUKE-104Imported, VACV_092Imported, VACV_CTGV_CM01_096Imported, VACV_IOC_B141_122Imported, VACV_IOC_B388_122Imported, VACV_TT10_116Imported, VACV_TT11_116Imported, VACV_TT12_116Imported, VACV_TT8_116Imported, VACV_TT9_116Imported
OrganismiVaccinia virusImported
Taxonomic identifieri10245 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirus
Proteomesi
  • UP000181371 Componenti: Genome
  • UP000153808 Componenti: Genome
  • UP000180811 Componenti: Genome
  • UP000181110 Componenti: Genome
  • UP000181073 Componenti: Genome
  • UP000181218 Componenti: Genome
  • UP000181292 Componenti: Genome
  • UP000147474 Componenti: Genome
  • UP000165418 Componenti: Genome
  • UP000181062 Componenti: Genome
  • UP000181099 Componenti: Genome
  • UP000125606 Componenti: Genome
  • UP000098152 Componenti: Genome
  • UP000108172 Componenti: Genome
  • UP000126037 Componenti: Genome
  • UP000181056 Componenti: Genome
  • UP000180962 Componenti: Genome
  • UP000181438 Componenti: Genome
  • UP000171434 Componenti: Genome
  • UP000181523 Componenti: Genome
  • UP000097422 Componenti: Genome
  • UP000181118 Componenti: Genome
  • UP000148654 Componenti: Genome
  • UP000181484 Componenti: Genome
  • UP000181235 Componenti: Genome
  • UP000181229 Componenti: Genome
  • UP000167479 Componenti: Genome
  • UP000181087 Componenti: Genome
  • UP000181537 Componenti: Genome
  • UP000136774 Componenti: Genome
  • UP000181589 Componenti: Genome
  • UP000148425 Componenti: Genome
  • UP000181416 Componenti: Genome
  • UP000173158 Componenti: Genome
  • UP000181601 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

  • virion Source: UniProtKB-UniRule

Keywords - Cellular componenti

DNA-directed RNA polymeraseUniRule annotationImported, VirionUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the poxviridae DNA-directed RNA polymerase 22 kDa subunit family.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR007937 RNA_Pol_22kDa_poxvir
PfamiView protein in Pfam
PF05273 Pox_RNA_Pol_22, 1 hit
PIRSFiPIRSF000744 RPO22, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD011187 RNA_Pol_22kDa_poxvir, 1 hit

Sequencei

Sequence statusi: Complete.

A4GDF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQYNVKYLA KILCLKTEIA RDPYAVINRN VLLRYTTDIE YNDLVTLITV
60 70 80 90 100
RHKIDSMKTV FQVFNESSIN YTPVDDDYGE PIIITSYLQK GHNKFPVNFL
110 120 130 140 150
YIDVVISDLF PSFVRLDTTE TNIVNSVLQT GDGKKTLRLP KMLETEIVVK
160 170 180
ILYRPNIPLK IVRFFRNNMV TGVEIADRSV ISVAD
Length:185
Mass (Da):21,342
Last modified:May 10, 2017 - v1
Checksum:iE4A289D674B3B9E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY313848 Genomic DNA Translation: AAQ93193.1
AY313847 Genomic DNA Translation: AAR17939.1
AY678275 Genomic DNA Translation: AAW23507.1
AY678277 Genomic DNA Translation: AAW23789.1
DQ121394 Genomic DNA Translation: ABD52562.1
DQ377945 Genomic DNA Translation: ABD57626.1
DQ439815 Genomic DNA Translation: ABD98566.1
JN654976 Genomic DNA Translation: AEY72669.1
JN654977 Genomic DNA Translation: AEY72907.1
JN654978 Genomic DNA Translation: AEY73142.1
JN654979 Genomic DNA Translation: AEY73384.1
JN654980 Genomic DNA Translation: AEY73624.1
JN654981 Genomic DNA Translation: AEY73854.1
JN654982 Genomic DNA Translation: AEY74094.1
JN654983 Genomic DNA Translation: AEY74335.1
JN654984 Genomic DNA Translation: AEY74563.1
JN654985 Genomic DNA Translation: AEY74803.1
JN654986 Genomic DNA Translation: AEY75043.1
KC201194 Genomic DNA Translation: AGB75817.1
JX489135 Genomic DNA Translation: AGJ91264.1
JX489136 Genomic DNA Translation: AGJ91537.1
JX489137 Genomic DNA Translation: AGJ91807.1
JX489138 Genomic DNA Translation: AGJ92079.1
JX489139 Genomic DNA Translation: AGJ92354.1
KC207810 Genomic DNA Translation: AGK06565.1
KC207811 Genomic DNA Translation: AGK06778.1
KF179385 Genomic DNA Translation: AHB35734.1
KJ125438 Genomic DNA Translation: AIX98791.1
KJ125439 Genomic DNA Translation: AIX99013.1
KM044309 Genomic DNA Translation: AIX99215.1
KM044310 Genomic DNA Translation: AIX99420.1
KP233807 Genomic DNA Translation: AIZ72845.1
KT184690 Genomic DNA Translation: ALF05092.1
KT184691 Genomic DNA Translation: ALF05343.1
KT013210 Genomic DNA Translation: ALF36253.1
KX061501 Genomic DNA Translation: AND73930.1
KX781953 Genomic DNA Translation: AQY54870.1
RefSeqiYP_232978.1, NC_006998.1

Genome annotation databases

GeneIDi3707552
KEGGivg:3707552

Similar proteinsi

Entry informationi

Entry nameiA4GDF1_9POXV
AccessioniPrimary (citable) accession number: A4GDF1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: February 28, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health