A4GBW9 (A4GBW9_9INFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Neuraminidase EMBL ABO38057.1

Gene names

Name:

NA EMBL ABO38057.1

Organism

Influenza A virus (A/AA/Marton/1943(H1N1)) EMBL ABO38057.1

Taxonomic identifier

425552 [NCBI]

Taxonomic lineage

Viruses › ssRNA negative-strand viruses › Orthomyxoviridae › Influenzavirus A

Protein attributes

Sequence length	469 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. SAAS SAAS011040
Subunit structure	Homotetramer By similarity. SAAS SAAS011040

Ontologies

Keywords
Cellular component	Host cell membrane SAAS SAAS011040 Host membrane Membrane Virion SAAS SAAS011040
Domain	Transmembrane Transmembrane helix SAAS SAAS011040
Molecular function	Glycosidase SAAS SAAS011040 Hydrolase
PTM	Disulfide bond SAAS SAAS011040
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	host cell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW virion Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	exo-alpha-sialidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4GBW9 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 11CF082D83C518DF	FASTA	469	51,555
	10 20 30 40 50 60 MNPNQKIITI GSICMVVGII SLILQIGNII SIWISHSIQT GSQNHTGTCN QSIITYKNST 70 80 90 100 110 120 WVNQTYVNIS NTNVVAGKDT TSVILAGNSS LCPIRGWAIY SKDNGVRIGS KGDVFVIREP 130 140 150 160 170 180 FISCSHLECR TFFLTQGALL NDKHSNGTVK DRSPYRALMS CPVGEAPSPY NSRFESVAWS 190 200 210 220 230 240 ASACHDGMGW LTIGISGPDD GAVAVLKYNG IITETIKSWR KEILRTQESE CACVNGSCFT 250 260 270 280 290 300 IMTDGPSGGP ASYKIFKIEK GKVTKSIELD APNSHYEECS CYPDTGKVMC VCRDNWHGSN 310 320 330 340 350 360 RPWVSFDQNL DYQMGYICSG VFGDNPRPKD GKGNCGPVYV DGANGVKGFS YRYGNGVWIG 370 380 390 400 410 420 RTKSNSSRQG FEMIWDPNGW TETDSNFFVK QDVVAVTDWS GYSGSFVQHP ELTGLDCMRP 430 440 450 460 CFWVELIRGR PKEKTIWTSG SSISFCGVNS DTVDWSWPDG AELPFTIDK

References

[1]

"The NIAID Influenza Genome Sequencing Project." Ghedin E., Spiro D., Miller N., Zaborsky J., Feldblyum T., Subbu V., Shumway M., Sparenborg J., Groveman L., Halpin R., Sitz J., Koo H., Salzberg S.L., Webster R.G., Hoffmann E., Krauss S., Naeve C., Bao Y. , Bolotov P., Dernovoy D., Kiryutin B., Lipman D.J., Tatusova T. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: A/AA/Marton/1943 EMBL ABO38057.1.

[2]

The NIAID Influenza Genome Sequencing Consortium Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: A/AA/Marton/1943 EMBL ABO38057.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CY020287 Viral cRNA. Translation: ABO38057.1.
3D structure databases
ProteinModelPortal	A4GBW9.
SMR	A4GBW9. Positions 83-467.
ModBase	Search...
Protein family/group databases
CAZy	GH34. Glycoside Hydrolase Family 34.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001860. Glyco_hydro_34. IPR011040. Neuraminidase. [Graphical view]
Gene3D	G3DSA:2.120.10.10. Neuraminidase. 1 hit.
Pfam	PF00064. Neur. 1 hit. [Graphical view]
SUPFAM	SSF50939. Sialidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4GBW9_9INFA

Accession

Primary (citable) accession number: A4GBW9

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)