Skip Header

Contribute Send feedback
Read comments (?) or add your own

A4G887 (A4G887_HERAR) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401

Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401
Gene names
Name:msrA HAMAP MF_01401 EMBL CAL62724.1
Ordered Locus Names:HEAR2602
OrganismHerminiimonas arsenicoxydans [Complete proteome] [HAMAP]
Taxonomic identifier204773 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeHerminiimonas

Protein attributes

Sequence length179 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site121 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
A4G887 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: 94ED796DB01D6F94

FASTA17920,286
        10         20         30         40         50         60 
MTTEIATLGG GCFWCTEAVF QQMKGITAIE SGYTGGQVAN PSYEQICEGT TGHAEVVRLT 

        70         80         90        100        110        120 
FDPAVVSFRE ILEVFFTIHD PTTLNRQGND VGTQYRSVIY YHTPEQQDMA RHVMAEMANV 

       130        140        150        160        170 
WDAPIVTELS PAETYYKAED YHQNYFRQNP LQGYCAFIVA PKVAKFRQTF RDKIRADMS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU207211 Genomic DNA. Translation: CAL62724.1.
RefSeqYP_001100845.1. NC_009138.1.

3D structure databases

ProteinModelPortalA4G887.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4G887.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4929896.
GenomeReviewsGene locus HEAR2602 in contig CU207211_GR.
KEGGhar:HEAR2602.
NMPDRfig|204773.3.peg.2476.
PATRIC22115164. VBIHerArs17568_2441.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0225.
HOGENOMHBG748152.
OMAIDTEVGY.
PhylomeDBA4G887.
ProtClustDBCLSK967374.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4G887_HERAR
AccessionPrimary (citable) accession number: A4G887
Entry history
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)