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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Herminiimonas arsenicoxydans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciHARS204773:G1GI6-2284-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:HEAR2442
OrganismiHerminiimonas arsenicoxydans
Taxonomic identifieri204773 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeHerminiimonas
Proteomesi
  • UP000006697 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003043371 – 243Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST243

Proteomic databases

PRIDEiA4G7T5

Interactioni

Protein-protein interaction databases

STRINGi204773.HEAR2442

Structurei

3D structure databases

ProteinModelPortaliA4G7T5
SMRiA4G7T5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

A4G7T5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPWLEADDP FPNVSSALTE ADGAPGLLAA GADLSAERLL LAYQNGIFPW
60 70 80 90 100
FSEGQPILWW STDPRMVLFI QDFKISASLK KTLKKIDRSM IANGRWQIRF
110 120 130 140 150
DHAFEDVMRA CAAPRNGEAG TWISDDIIAG YTRLHRLGYA HSSELWLDDE
160 170 180 190 200
LVGGLYGVSI GNMFYGESMF TRVTDASKIA LAYLVRFLGS HGVSMIDCQQ
210 220 230 240
QTAHLASLGA MPISRTEFIS LLRQAIAAPQ IMDWKPIPMF EVN
Length:243
Mass (Da):27,031
Last modified:April 17, 2007 - v1
Checksum:i9946E6BBA0FF8259
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207211 Genomic DNA Translation: CAL62572.1
RefSeqiWP_011871833.1, NC_009138.1

Genome annotation databases

EnsemblBacteriaiCAL62572; CAL62572; HEAR2442
KEGGihar:HEAR2442

Similar proteinsi

Entry informationi

Entry nameiLFTR_HERAR
AccessioniPrimary (citable) accession number: A4G7T5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: April 17, 2007
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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