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A4G6U4 (A4G6U4_HERAR) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6,7-dimethyl-8-ribityllumazine synthase 2 HAMAP MF_00178
Short name=DMRL synthase 2 HAMAP MF_00178
Short name=Lumazine synthase 2 HAMAP MF_00178
EC=2.5.1.9 HAMAP MF_00178
Alternative name(s):
Riboflavin synthase beta chain 2 HAMAP MF_00178
Gene names
Name:ribH2 HAMAP MF_00178 EMBL CAL62231.1
Ordered Locus Names:HEAR2090
OrganismHerminiimonas arsenicoxydans [Complete proteome] [HAMAP]
Taxonomic identifier204773 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Oxalobacteraceae › Herminiimonas

Protein attributes

Sequence length167 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate yielding 6,7-dimethyl-8-lumazine By similarity. HAMAP MF_00178

Catalytic activity

2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine. HAMAP MF_00178

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2. HAMAP MF_00178

Sequence similarities

Belongs to the DMRL synthase family. HAMAP MF_00178

Ontologies

Keywords
   Biological processRiboflavin biosynthesis HAMAP MF_00178
   Molecular functionTransferase HAMAP MF_00178 EMBL CAL62231.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processriboflavin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentriboflavin synthase complex

Inferred from electronic annotation. Source: InterPro

   Molecular functionriboflavin synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A4G6U4 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: 9764C9393C8378F8

FASTA16718,494
        10         20         30         40         50         60 
MQHAIDIKAK SAARRIAFIQ ASWHKEIVDQ CRIAFVEEMA ARGYSADVID FFEVAGAFEI 

        70         80         90        100        110        120 
PLHAKVLAKS GRYAAIVGTG LVVDGGVYRH EFVSQAVISG LMQVQLETEV PVISAVLTPH 

       130        140        150        160 
HFHSHDEHQG FFFQHFLVKG KEAAHACADT IQRLQQIDAM TQERIAA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU207211 Genomic DNA. Translation: CAL62231.1.
RefSeqYP_001100354.1. NC_009138.1.

3D structure databases

ProteinModelPortalA4G6U4.
SMRA4G6U4. Positions 15-157.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4G6U4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4931822.
GenomeReviewsGene locus HEAR2090 in contig CU207211_GR.
KEGGhar:HEAR2090.
NMPDRfig|204773.3.peg.1985.
PATRIC22114224. VBIHerArs17568_1977.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0054.
HOGENOMHBG311126.
OMARRYTAIV.
ProtClustDBPRK12419.

Family and domain databases

HAMAPMF_00178. Lumazine_synth.
[Tree]
InterProIPR002180. DMRL_synthase.
[Graphical view]
Gene3DG3DSA:3.40.50.960. DMRL_synthase. 1 hit.
KOK00794.
PANTHERPTHR21058. DMRL_synthase. 1 hit.
PfamPF00885. DMRL_synthase. 1 hit.
[Graphical view]
SUPFAMSSF52121. DMRL_synthase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4G6U4_HERAR
AccessionPrimary (citable) accession number: A4G6U4
Entry history
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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