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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Herminiimonas arsenicoxydans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi8 – 81Divalent metal cationUniRule annotation
Metal bindingi9 – 91Divalent metal cationUniRule annotation
Metal bindingi39 – 391Divalent metal cationUniRule annotation
Metal bindingi91 – 911Divalent metal cationUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHARS204773:GJCA-1209-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:HEAR1254
OrganismiHerminiimonas arsenicoxydans
Taxonomic identifieri204773 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeHerminiimonas
Proteomesi
  • UP000006697 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2452455'-nucleotidase SurEPRO_1000007739Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi204773.HEAR1254.

Structurei

3D structure databases

ProteinModelPortaliA4G4J2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122500.
KOiK03787.
OMAiNLNIPPC.
OrthoDBiPOG091H01CP.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

A4G4J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILISNDDG YLAPGLIALA DALAPIADIV VVAPDSNRSG SSNSLTLDRP
60 70 80 90 100
LSVYQASNGF YFINGTPSDC VHIALTGIMS FRPDLIVSGI NQGQNMGDDT
110 120 130 140 150
LYSGTVAAAT EGHLFGIPAI AFSQLEKGWA ELKSAARVAR DIVERRFETL
160 170 180 190 200
PENFLLNVNI PNLPYEQLKP AVATRLGRRH QSEAVIKAQD PHGRDIYWIG
210 220 230 240
PSGGQKDAGE GTDFHATAQG HVSITPLQID LTQNAQLAAL KKVLA
Length:245
Mass (Da):26,200
Last modified:April 17, 2007 - v1
Checksum:i577F535D7E9B4F93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207211 Genomic DNA. Translation: CAL61429.1.
RefSeqiWP_011870764.1. NC_009138.1.

Genome annotation databases

EnsemblBacteriaiCAL61429; CAL61429; HEAR1254.
KEGGihar:HEAR1254.
PATRICi22112612. VBIHerArs17568_1183.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207211 Genomic DNA. Translation: CAL61429.1.
RefSeqiWP_011870764.1. NC_009138.1.

3D structure databases

ProteinModelPortaliA4G4J2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi204773.HEAR1254.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL61429; CAL61429; HEAR1254.
KEGGihar:HEAR1254.
PATRICi22112612. VBIHerArs17568_1183.

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122500.
KOiK03787.
OMAiNLNIPPC.
OrthoDBiPOG091H01CP.

Enzyme and pathway databases

BioCyciHARS204773:GJCA-1209-MONOMER.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSURE_HERAR
AccessioniPrimary (citable) accession number: A4G4J2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: September 7, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.