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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Herminiimonas arsenicoxydans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei157 – 1571UniRule annotation
Active sitei596 – 5961UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciHARS204773:GJCA-964-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:HEAR1006Imported
OrganismiHerminiimonas arsenicoxydansImported
Taxonomic identifieri204773 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeHerminiimonas
ProteomesiUP000006697 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi204773.HEAR1006.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4G3V1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKQLKTPTR TLTSSADKDA PLKEDIRLLG RLLGDVLRDQ QGDAVFEIVE
60 70 80 90 100
TIRQTAVRFR RESDVQAGAE LNKLLKKLTR EQTISVVRAF SYFSHLANIA
110 120 130 140 150
EDQHHNRRRR AHLLAGSQPQ DGSVACALEK LHDAGVSGAT VRKFFKDALI
160 170 180 190 200
SPVLTAHPTE VQRKSILDAE HDIASLLAAR DLPMTAKERA ENTERIHSRV
210 220 230 240 250
TTLWQTRLLR YTKLTVEDEI NNALSYYRMT FLRELPALYE DIESEIAERF
260 270 280 290 300
PQRASSASRE QPLYIQMGSW IGGDRDGNPN VNGDTMQLAL ARQSTTILEF
310 320 330 340 350
YLEEVHALGA ELSISTFLAG VSPEVQALAD KSPDTSEHRT DEQYRRALIG
360 370 380 390 400
MYARLAATAR AQGATVLRKE IGSAPAYENA AEFSSDLQAL ADSLKARHGA
410 420 430 440 450
ALIKPRLASL LRAAEIFGFH LATLDMRQSS DVHERVLSEL FKCAQVESAY
460 470 480 490 500
AALPEEKKVA LLLAELDHPR LLYSPYVDYS EETNSELSIL RAASDIRKRY
510 520 530 540 550
GARAIRNYII SHTETVSDML EVLLLQRETG LLRLDTDKDS VGQLELMVIP
560 570 580 590 600
LFETIPDLRL AATIMEQVMA IPQVRKLIAK QGHLQEVMLG YSDSNKDGGF
610 620 630 640 650
LTSNWELYKA ETQLVEVFNN AGVKLRLFHG RGGTVGRGGG PSYEAILAQP
660 670 680 690 700
PGTVNGQIRL TEQGEIIASK FSNPEIGRRN LALLVAATLE ASLIPAPSET
710 720 730 740 750
RHAKKLAEFE SVMGELSELA YKAYRNLVYE TPGFTDYFFA ATPIAEIAEL
760 770 780 790 800
NIGSRPASRK ATRRIEDLRA IPWGFSWGQC RLLLPGWYGF GSAIELWLTQ
810 820 830 840 850
GDNKAKRVAT LRAMLKEWPF FATLLSNMDM VLSKTDLAVA SRYAELVSDK
860 870 880 890 900
KLRNSIFKRI VNEHERTSAS LTLITGKKER LANNPLLARS IKNRFAYLDP
910 920 930 940
LNHLQVELIK RHRATMNGGD ADDRVRRGIH LSINGIAAGL RNTG
Length:944
Mass (Da):105,215
Last modified:April 17, 2007 - v1
Checksum:i903A78F88F551AED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207211 Genomic DNA. Translation: CAL61188.1.
RefSeqiWP_011870525.1. NC_009138.1.
YP_001099315.1. NC_009138.1.

Genome annotation databases

EnsemblBacteriaiCAL61188; CAL61188; HEAR1006.
KEGGihar:HEAR1006.
PATRICi22112106. VBIHerArs17568_0933.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207211 Genomic DNA. Translation: CAL61188.1.
RefSeqiWP_011870525.1. NC_009138.1.
YP_001099315.1. NC_009138.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi204773.HEAR1006.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL61188; CAL61188; HEAR1006.
KEGGihar:HEAR1006.
PATRICi22112106. VBIHerArs17568_0933.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciHARS204773:GJCA-964-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ULPAs1Imported.

Entry informationi

Entry nameiA4G3V1_HERAR
AccessioniPrimary (citable) accession number: A4G3V1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: April 29, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.