A4G1F0 (A4G1F0_HERAR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dethiobiotin synthetase (Dethiobiotin synthase) (DTB synthetase) (DTBS) EMBL CAL60337.1
EC=6.3.3.3 EMBL CAL60337.1

Gene names

Name:	bioD EMBL CAL60337.1
Ordered Locus Names:	HEAR0101

Organism

Herminiimonas arsenicoxydans [Complete proteome] [HAMAP]

Taxonomic identifier

204773 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Oxalobacteraceae › Herminiimonas

Protein attributes

Sequence length	250 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472
Catalytic activity	ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472
Cofactor	Magnesium By similarity. SAAS SAAS004472
Pathway	Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472
Subcellular location	Cytoplasm By similarity SAAS SAAS004472.

Ontologies

Keywords
Biological process	Biotin biosynthesis SAAS SAAS004472
Cellular component	Cytoplasm SAAS SAAS004472
Ligand	ATP-binding SAAS SAAS004472 Magnesium SAAS SAAS004472 Metal-binding SAAS SAAS004472 Nucleotide-binding
Molecular function	Ligase SAAS SAAS004472 EMBL CAL60337.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	biotin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dethiobiotin synthase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4G1F0 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: A76A4D07D02102E0	FASTA	250	25,854
	10 20 30 40 50 60 MYFIKLKRKH DMTASFSCFV TGTDTEIGKT LISTAILHAL VQGGVRAAAI KTVAAGATAI 70 80 90 100 110 120 QTAGIEVWHN DDADALAQAA NVVLPTELAT PYLLHAAAAP HVAAKLQNIA LEIAHIKRCY 130 140 150 160 170 180 AQVAEMADAV VVEGVGGFCV PLSDDADMAD CARQLDLPVI MVVGLRLGCL SHALLTAEAI 190 200 210 220 230 240 AARGLKLVGW VANTVDAGMP FAEDNVAALT ARLPAPLLGC VPRLAAPLPA AAAAYLDFSC 250 LPGWPGTPTV

References

[1]

"A tale of two oxidation states: bacterial colonization of arsenic-rich environments." Muller D., Medigue C., Koechler S., Barbe V., Barakat M., Talla E., Bonnefoy V., Krin E., Arsene-Ploetze F., Carapito C., Chandler M., Cournoyer B., Cruveiller S., Dossat C., Duval S., Heymann M., Leize E., Lieutaud A. , Lievremont D., Makita Y., Mangenot S., Nitschke W., Ortet P., Perdrial N., Schoepp B., Siguier P., Simeonova D.D., Rouy Z., Segurens B., Turlin E., Vallenet D., van Dorsselaer A., Weiss S., Weissenbach J., Lett M.-C., Danchin A., Bertin P.N. PLoS Genet. 3:518-530(2007) [PubMed: 17432936] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ULPAs1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU207211 Genomic DNA. Translation: CAL60337.1.
RefSeq	YP_001098466.1. NC_009138.1.
3D structure databases
ProteinModelPortal	A4G1F0.
ModBase	Search...
Protein-protein interaction databases
STRING	A4G1F0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4930513.
GenomeReviews	Gene locus HEAR0101 in contig CU207211_GR.
KEGG	har:HEAR0101.
NMPDR	fig|204773.3.peg.97.
PATRIC	22110400. VBIHerArs17568_0100.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0132.
HOGENOM	HBG650065.
OMA	ANCVDPN.
PhylomeDB	A4G1F0.
ProtClustDB	CLSK966460.
Family and domain databases
HAMAP	MF_00336. BioD. [Tree]
InterPro	IPR002586. CbiA_P_synth. IPR004472. DTB_synth_BioD. [Graphical view]
KO	K01935.
Pfam	PF01656. CbiA. 1 hit. [Graphical view]
PIRSF	PIRSF006755. DTB_synth. 1 hit.
TIGRFAMs	TIGR00347. BioD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4G1F0_HERAR

Accession

Primary (citable) accession number: A4G1F0

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)