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A4G1E2

- SYR_HERAR

UniProt

A4G1E2 - SYR_HERAR

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Herminiimonas arsenicoxydans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHARS204773:GJCA-90-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:HEAR0093
OrganismiHerminiimonas arsenicoxydans
Taxonomic identifieri204773 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeHerminiimonas
ProteomesiUP000006697: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 577577Arginine--tRNA ligasePRO_1000018042Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi204773.HEAR0093.

Structurei

3D structure databases

ProteinModelPortaliA4G1E2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi132 – 14211"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiMEHMGFG.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4G1E2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLAAQKQRIT ELFQAAVAPL VAGTELNPTV TLERPRDPSH GDVACNLAMQ
60 70 80 90 100
IAKPLKKNPR EVAQVLVAAL LDNPANRDLI ESAEIAGPGF INLRLTPASR
110 120 130 140 150
QSVVKTVLQQ GAQYGKSNLG AGKKVIIEFV SANPTGPLHV GHGRQGALGD
160 170 180 190 200
AMSSLFDAQG YAVTREFYYN DAGVQIATLA TSVQARARGL KPGAEGWPES
210 220 230 240 250
AYNGDYIQDI ANDFLAKKTV SASDGLPVTA SGDIDDIESI RAFAVAYLRR
260 270 280 290 300
EQDLDLQAFG VKFDNYYLES SLYNDGKVAA TVDALIKADK TYELDGALWL
310 320 330 340 350
RTTDYRDDKD RVMKKSDGTY TYFVPDVAYH TVKWQRGFTQ AINVQGSDHH
360 370 380 390 400
GTIARVRAGL QALDIGIPQG YPDYVLHKMV TVMRNGEEVK ISKRAGSYVT
410 420 430 440 450
LRDLIEWSNG ETVEGQERDL TRGRDAVRFF LISRKADTEF VFDVDVALSQ
460 470 480 490 500
SDENPVYYVQ YAHARICSVL AQWTDGDEAA LLDVDLSPLT APREAALLAK
510 520 530 540 550
LAEYPEALQR ALEELGPHQV AFYLRDLAAE LHSYYNAERV LVDDVALKMA
560 570
RLTLMHATRQ VLRNGLALIG VSAPARM
Length:577
Mass (Da):63,353
Last modified:April 17, 2007 - v1
Checksum:i997E7503CFEBB7CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207211 Genomic DNA. Translation: CAL60329.1.
RefSeqiWP_011869678.1. NC_009138.1.
YP_001098458.1. NC_009138.1.

Genome annotation databases

EnsemblBacteriaiCAL60329; CAL60329; HEAR0093.
GeneIDi4930039.
KEGGihar:HEAR0093.
PATRICi22110382. VBIHerArs17568_0091.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU207211 Genomic DNA. Translation: CAL60329.1 .
RefSeqi WP_011869678.1. NC_009138.1.
YP_001098458.1. NC_009138.1.

3D structure databases

ProteinModelPortali A4G1E2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 204773.HEAR0093.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL60329 ; CAL60329 ; HEAR0093 .
GeneIDi 4930039.
KEGGi har:HEAR0093.
PATRICi 22110382. VBIHerArs17568_0091.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247214.
KOi K01887.
OMAi MEHMGFG.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci HARS204773:GJCA-90-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ULPAs1.

Entry informationi

Entry nameiSYR_HERAR
AccessioniPrimary (citable) accession number: A4G1E2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3