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A4G1E2 (SYR_HERAR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:HEAR0093
OrganismHerminiimonas arsenicoxydans [Complete proteome] [HAMAP]
Taxonomic identifier204773 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeHerminiimonas

Protein attributes

Sequence length577 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 577577Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018042

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A4G1E2 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: 997E7503CFEBB7CB

FASTA57763,353
        10         20         30         40         50         60 
MLAAQKQRIT ELFQAAVAPL VAGTELNPTV TLERPRDPSH GDVACNLAMQ IAKPLKKNPR 

        70         80         90        100        110        120 
EVAQVLVAAL LDNPANRDLI ESAEIAGPGF INLRLTPASR QSVVKTVLQQ GAQYGKSNLG 

       130        140        150        160        170        180 
AGKKVIIEFV SANPTGPLHV GHGRQGALGD AMSSLFDAQG YAVTREFYYN DAGVQIATLA 

       190        200        210        220        230        240 
TSVQARARGL KPGAEGWPES AYNGDYIQDI ANDFLAKKTV SASDGLPVTA SGDIDDIESI 

       250        260        270        280        290        300 
RAFAVAYLRR EQDLDLQAFG VKFDNYYLES SLYNDGKVAA TVDALIKADK TYELDGALWL 

       310        320        330        340        350        360 
RTTDYRDDKD RVMKKSDGTY TYFVPDVAYH TVKWQRGFTQ AINVQGSDHH GTIARVRAGL 

       370        380        390        400        410        420 
QALDIGIPQG YPDYVLHKMV TVMRNGEEVK ISKRAGSYVT LRDLIEWSNG ETVEGQERDL 

       430        440        450        460        470        480 
TRGRDAVRFF LISRKADTEF VFDVDVALSQ SDENPVYYVQ YAHARICSVL AQWTDGDEAA 

       490        500        510        520        530        540 
LLDVDLSPLT APREAALLAK LAEYPEALQR ALEELGPHQV AFYLRDLAAE LHSYYNAERV 

       550        560        570 
LVDDVALKMA RLTLMHATRQ VLRNGLALIG VSAPARM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU207211 Genomic DNA. Translation: CAL60329.1.
RefSeqYP_001098458.1. NC_009138.1.

3D structure databases

ProteinModelPortalA4G1E2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204773.HEAR0093.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL60329; CAL60329; HEAR0093.
GeneID4930039.
KEGGhar:HEAR0093.
PATRIC22110382. VBIHerArs17568_0091.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycHARS204773:GJCA-90-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_HERAR
AccessionPrimary (citable) accession number: A4G1E2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries