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A4G168 (PNCB_HERAR) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:HEAR0018
OrganismHerminiimonas arsenicoxydans [Complete proteome] [HAMAP]
Taxonomic identifier204773 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeHerminiimonas

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000212085

Sequences

Sequence LengthMass (Da)Tools
A4G168 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: B139362578BB4CD7

FASTA39745,514
        10         20         30         40         50         60 
MPPIVNNLLE NDLYKFTMWQ ALLHSHPEAQ TEYEFVCRNA PAYPLSELKA DVERELDHLC 

        70         80         90        100        110        120 
TLAFRDDELL YLRSLRFMKS DFVDFLTVFR FQRKFITVAA DGPALRIRAI GPQVHVMGFE 

       130        140        150        160        170        180 
IFVLCIVNEL YLRRFDQQAS LTEARRRLQE KIRLLKNFGK EATRKNPFEF FDFGVRRRFS 

       190        200        210        220        230        240 
AAWHEEVVVT LAREVPQYFT GTSNVHLAKK YGLTPIGTMA HEYLQAYQSF GVRLRDFQKA 

       250        260        270        280        290        300 
ALEDWVQEYR GDLGIALTDV VGMDAFLADF DLYFAKLFDG LRHDSGDPIE WGEKALAHYA 

       310        320        330        340        350        360 
RLRIDAGSKR LVFSDALDLP GAFSLYRHFA DRTLTGFGIG TNLSNDTGIP ALNIVMKLMA 

       370        380        390 
CNGQPVAKLS DSAGKTLCRD ETFLAYLRQV FHHPAVK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU207211 Genomic DNA. Translation: CAL60255.1.
RefSeqYP_001098384.1. NC_009138.1.

3D structure databases

ProteinModelPortalA4G168.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING204773.HEAR0018.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL60255; CAL60255; HEAR0018.
GeneID4933037.
KEGGhar:HEAR0018.
PATRIC22110226. VBIHerArs17568_0013.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMALYKFTMW.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycHARS204773:GJCA-15-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_HERAR
AccessionPrimary (citable) accession number: A4G168
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: April 17, 2007
Last modified: March 19, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways