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A4FYT6 (A4FYT6_METM5) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP-Rule MF_00137

EC=6.3.2.6 HAMAP-Rule MF_00137
Alternative name(s):
SAICAR synthetase HAMAP-Rule MF_00137
Gene names
Name:purC HAMAP-Rule MF_00137
Ordered Locus Names:MmarC5_1067 EMBL ABO35370.1
OrganismMethanococcus maripaludis (strain C5 / ATCC BAA-1333) [Complete proteome] [HAMAP] EMBL ABO35370.1
Taxonomic identifier402880 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP-Rule MF_00137

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP-Rule MF_00137

Sequence similarities

Belongs to the SAICAR synthetase family. HAMAP-Rule MF_00137

Sequences

Sequence LengthMass (Da)Tools
A4FYT6 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: 681A75F17A923704

FASTA24527,699
        10         20         30         40         50         60 
MSYDISKITA KEPIYAGKAK SIYKIEENEK EVLVEFRDDI TAGNGAKHDV KSGKGYLNTL 

        70         80         90        100        110        120 
ISNELFKILE QNNVPTHLIE YIEPNHMIAK NVKIIPLEVI VRNIAAGSLC KKYPFEQGQV 

       130        140        150        160        170        180 
LKTAVTQFDY KNDDYGDPML NNEITIELGL ATEEELVEIK KLALKVNDVL KGFFDEKGII 

       190        200        210        220        230        240 
LVDFKIEVGK TVDGDIVVAD EISPDTMRLW DKETKDVLDK DVFRKDLGDV LEKYKTVAKR 


IGCLK 

« Hide

References

[1]"Complete sequence of chromosome of Methanococcus maripaludis C5."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Detter J.C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C5 / ATCC BAA-1333.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000609 Genomic DNA. Translation: ABO35370.1.
RefSeqYP_001097585.1. NC_009135.1.

3D structure databases

ProteinModelPortalA4FYT6.
SMRA4FYT6. Positions 1-244.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING402880.MmarC5_1067.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABO35370; ABO35370; MmarC5_1067.
GeneID4927538.
KEGGmmq:MmarC5_1067.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0152.
HOGENOMHOG000082629.
KOK01923.
OMAFNAQKRG.
ProtClustDBPRK09362.

Enzyme and pathway databases

BioCycMMAR402880:GJ2R-1081-MONOMER.
UniPathwayUPA00074; UER00131.

Family and domain databases

Gene3D3.30.470.20. 1 hit.
HAMAPMF_00137. SAICAR_synth.
InterProIPR013816. ATP_grasp_subdomain_2.
IPR028923. SAICAR_synt/ADE2_N.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
PfamPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsTIGR00081. purC. 1 hit.
PROSITEPS01057. SAICAR_SYNTHETASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4FYT6_METM5
AccessionPrimary (citable) accession number: A4FYT6
Entry history
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: April 16, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)