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A4FYT6

- A4FYT6_METM5

UniProt

A4FYT6 - A4FYT6_METM5

Protein

Phosphoribosylaminoimidazole-succinocarboxamide synthase

Gene

purC

Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (17 Apr 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    Purine biosynthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMMAR402880:GJ2R-1081-MONOMER.
    UniPathwayiUPA00074; UER00131.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylaminoimidazole-succinocarboxamide synthaseUniRule annotation (EC:6.3.2.6UniRule annotation)
    Alternative name(s):
    SAICAR synthetaseUniRule annotation
    Gene namesi
    Name:purCUniRule annotation
    Ordered Locus Names:MmarC5_1067Imported
    OrganismiMethanococcus maripaludis (strain C5 / ATCC BAA-1333)Imported
    Taxonomic identifieri402880 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
    ProteomesiUP000000253: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi402880.MmarC5_1067.

    Structurei

    3D structure databases

    ProteinModelPortaliA4FYT6.
    SMRiA4FYT6. Positions 1-244.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SAICAR synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0152.
    HOGENOMiHOG000082629.
    KOiK01923.
    OMAiYKSDEYG.

    Family and domain databases

    Gene3Di3.30.470.20. 1 hit.
    HAMAPiMF_00137. SAICAR_synth.
    InterProiIPR013816. ATP_grasp_subdomain_2.
    IPR028923. SAICAR_synt/ADE2_N.
    IPR001636. SAICAR_synth.
    IPR018236. SAICAR_synthetase_CS.
    [Graphical view]
    PfamiPF01259. SAICAR_synt. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00081. purC. 1 hit.
    PROSITEiPS01057. SAICAR_SYNTHETASE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4FYT6-1 [UniParc]FASTAAdd to Basket

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    MSYDISKITA KEPIYAGKAK SIYKIEENEK EVLVEFRDDI TAGNGAKHDV    50
    KSGKGYLNTL ISNELFKILE QNNVPTHLIE YIEPNHMIAK NVKIIPLEVI 100
    VRNIAAGSLC KKYPFEQGQV LKTAVTQFDY KNDDYGDPML NNEITIELGL 150
    ATEEELVEIK KLALKVNDVL KGFFDEKGII LVDFKIEVGK TVDGDIVVAD 200
    EISPDTMRLW DKETKDVLDK DVFRKDLGDV LEKYKTVAKR IGCLK 245
    Length:245
    Mass (Da):27,699
    Last modified:April 17, 2007 - v1
    Checksum:i681A75F17A923704
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000609 Genomic DNA. Translation: ABO35370.1.
    RefSeqiWP_011868823.1. NC_009135.1.
    YP_001097585.1. NC_009135.1.

    Genome annotation databases

    EnsemblBacteriaiABO35370; ABO35370; MmarC5_1067.
    GeneIDi4927538.
    KEGGimmq:MmarC5_1067.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000609 Genomic DNA. Translation: ABO35370.1 .
    RefSeqi WP_011868823.1. NC_009135.1.
    YP_001097585.1. NC_009135.1.

    3D structure databases

    ProteinModelPortali A4FYT6.
    SMRi A4FYT6. Positions 1-244.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 402880.MmarC5_1067.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABO35370 ; ABO35370 ; MmarC5_1067 .
    GeneIDi 4927538.
    KEGGi mmq:MmarC5_1067.

    Phylogenomic databases

    eggNOGi COG0152.
    HOGENOMi HOG000082629.
    KOi K01923.
    OMAi YKSDEYG.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00131 .
    BioCyci MMAR402880:GJ2R-1081-MONOMER.

    Family and domain databases

    Gene3Di 3.30.470.20. 1 hit.
    HAMAPi MF_00137. SAICAR_synth.
    InterProi IPR013816. ATP_grasp_subdomain_2.
    IPR028923. SAICAR_synt/ADE2_N.
    IPR001636. SAICAR_synth.
    IPR018236. SAICAR_synthetase_CS.
    [Graphical view ]
    Pfami PF01259. SAICAR_synt. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00081. purC. 1 hit.
    PROSITEi PS01057. SAICAR_SYNTHETASE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C5 / ATCC BAA-1333Imported.

    Entry informationi

    Entry nameiA4FYT6_METM5
    AccessioniPrimary (citable) accession number: A4FYT6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 17, 2007
    Last sequence update: April 17, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3