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A4FYT6 (A4FYT6_METM5) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP MF_00137

EC=6.3.2.6 HAMAP MF_00137
Alternative name(s):
SAICAR synthetase HAMAP MF_00137
Gene names
Name:purC HAMAP MF_00137
Ordered Locus Names:MmarC5_1067
OrganismMethanococcus maripaludis (strain C5 / ATCC BAA-1333) [Complete proteome] [HAMAP]
Taxonomic identifier402880 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP MF_00137

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP MF_00137

Sequence similarities

Belongs to the SAICAR synthetase family. HAMAP MF_00137 RuleBase RU004193

Sequences

Sequence LengthMass (Da)Tools
A4FYT6 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: 681A75F17A923704

FASTA24527,699
        10         20         30         40         50         60 
MSYDISKITA KEPIYAGKAK SIYKIEENEK EVLVEFRDDI TAGNGAKHDV KSGKGYLNTL 

        70         80         90        100        110        120 
ISNELFKILE QNNVPTHLIE YIEPNHMIAK NVKIIPLEVI VRNIAAGSLC KKYPFEQGQV 

       130        140        150        160        170        180 
LKTAVTQFDY KNDDYGDPML NNEITIELGL ATEEELVEIK KLALKVNDVL KGFFDEKGII 

       190        200        210        220        230        240 
LVDFKIEVGK TVDGDIVVAD EISPDTMRLW DKETKDVLDK DVFRKDLGDV LEKYKTVAKR 


IGCLK 

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References

[1]"Complete sequence of chromosome of Methanococcus maripaludis C5."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Detter J.C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C5 / ATCC BAA-1333.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000609 Genomic DNA. Translation: ABO35370.1.
RefSeqYP_001097585.1. NC_009135.1.

3D structure databases

ProteinModelPortalA4FYT6.
SMRA4FYT6. Positions 1-244.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4FYT6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4927538.
GenomeReviewsGene locus MmarC5_1067 in contig CP000609_GR.
KEGGmmq:MmarC5_1067.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG05989.
HOGENOMHBG306070.
OMAYKDDALG.
PhylomeDBA4FYT6.
ProtClustDBPRK09362.

Family and domain databases

HAMAPMF_00137. SAICAR_synth.
[Tree]
InterProIPR013816. ATP_grasp_subdomain_2.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
Gene3DG3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KOK01923.
PANTHERPTHR11609. SAICAR_synt. 1 hit.
PfamPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsTIGR00081. PurC. 1 hit.
PROSITEPS01057. SAICAR_SYNTHETASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4FYT6_METM5
AccessionPrimary (citable) accession number: A4FYT6
Entry history
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: November 16, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)