Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A4FXV4

- RNP4_METM5

UniProt

A4FXV4 - RNP4_METM5

Protein

Ribonuclease P protein component 4

Gene

rnp4

Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
  1. Functioni

    Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi65 – 651ZincUniRule annotation
    Metal bindingi68 – 681ZincUniRule annotation
    Metal bindingi94 – 941ZincUniRule annotation
    Metal bindingi97 – 971ZincUniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-HAMAP
    2. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. tRNA 5'-leader removal Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciMMAR402880:GJ2R-741-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein component 4UniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P component 4UniRule annotation
    Alternative name(s):
    Rpp21UniRule annotation
    Gene namesi
    Name:rnp4UniRule annotation
    Ordered Locus Names:MmarC5_0728
    OrganismiMethanococcus maripaludis (strain C5 / ATCC BAA-1333)
    Taxonomic identifieri402880 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
    ProteomesiUP000000253: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. ribonuclease P complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 110110Ribonuclease P protein component 4PRO_1000046632Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi402880.MmarC5_0728.

    Structurei

    3D structure databases

    ProteinModelPortaliA4FXV4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eukaryotic/archaeal RNase P protein component 4 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2023.
    HOGENOMiHOG000230709.
    KOiK03540.
    OMAiPRKWKRR.

    Family and domain databases

    HAMAPiMF_00757. RNase_P_4.
    InterProiIPR016432. RNase_P_comp-4.
    IPR007175. Rpr2.
    [Graphical view]
    PANTHERiPTHR14742. PTHR14742. 1 hit.
    PfamiPF04032. Rpr2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF004878. RNase_P_4. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A4FXV4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLKKKFLEK SKKIAEERID VLMNLAEKES KAGKIDRSKN YVLLGKKIAM    50
    RMRMPYPKEW KRRICKNCGS FLIYGKNARV RTKAKNYPHV VITCLECNSI 100
    TRIPIKSEKK 110
    Length:110
    Mass (Da):12,932
    Last modified:April 17, 2007 - v1
    Checksum:i5E248CBCD4D95883
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000609 Genomic DNA. Translation: ABO35038.1.
    RefSeqiWP_011868492.1. NC_009135.1.
    YP_001097253.1. NC_009135.1.

    Genome annotation databases

    EnsemblBacteriaiABO35038; ABO35038; MmarC5_0728.
    GeneIDi4928715.
    KEGGimmq:MmarC5_0728.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000609 Genomic DNA. Translation: ABO35038.1 .
    RefSeqi WP_011868492.1. NC_009135.1.
    YP_001097253.1. NC_009135.1.

    3D structure databases

    ProteinModelPortali A4FXV4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 402880.MmarC5_0728.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABO35038 ; ABO35038 ; MmarC5_0728 .
    GeneIDi 4928715.
    KEGGi mmq:MmarC5_0728.

    Phylogenomic databases

    eggNOGi COG2023.
    HOGENOMi HOG000230709.
    KOi K03540.
    OMAi PRKWKRR.

    Enzyme and pathway databases

    BioCyci MMAR402880:GJ2R-741-MONOMER.

    Family and domain databases

    HAMAPi MF_00757. RNase_P_4.
    InterProi IPR016432. RNase_P_comp-4.
    IPR007175. Rpr2.
    [Graphical view ]
    PANTHERi PTHR14742. PTHR14742. 1 hit.
    Pfami PF04032. Rpr2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF004878. RNase_P_4. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C5 / ATCC BAA-1333.

    Entry informationi

    Entry nameiRNP4_METM5
    AccessioniPrimary (citable) accession number: A4FXV4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: April 17, 2007
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3