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Protein

Ribonuclease P protein component 2

Gene

rnp2

Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processtRNA processing

Enzyme and pathway databases

BioCyciMMAR402880:G1G8G-696-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 2UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 2UniRule annotation
Alternative name(s):
Pop5UniRule annotation
Gene namesi
Name:rnp2UniRule annotation
Ordered Locus Names:MmarC5_0686
OrganismiMethanococcus maripaludis (strain C5 / ATCC BAA-1333)
Taxonomic identifieri402880 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000000253 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000466221 – 130Ribonuclease P protein component 2Add BLAST130

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi402880.MmarC5_0686

Structurei

3D structure databases

ProteinModelPortaliA4FXR3
SMRiA4FXR3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01365 Archaea
COG1369 LUCA
HOGENOMiHOG000286243
KOiK03537
OMAiNPWLIDY
OrthoDBiPOG093Z0EPO

Family and domain databases

Gene3Di3.30.70.3250, 1 hit
HAMAPiMF_00755 RNase_P_2, 1 hit
InterProiView protein in InterPro
IPR002759 RNase_P/MRP_subunit
IPR016434 RNase_P_comp-2
IPR038085 Rnp2-like_sf
PfamiView protein in Pfam
PF01900 RNase_P_Rpp14, 1 hit
PIRSFiPIRSF004952 RNase_P_2, 1 hit
SUPFAMiSSF160350 SSF160350, 1 hit

Sequencei

Sequence statusi: Complete.

A4FXR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKTLPPTLR EKKRYVALEI IFEEELFQKD VIAIVRNALM NYSGVLGCSR
60 70 80 90 100
TNPWLIDYNH PYGILRISRE EVNNLRSSLS LTNEHRKKPI NIHIIGISNS
110 120 130
VKHVREKFLH VPHEPYYKVI QKLKKKGPKK
Length:130
Mass (Da):15,270
Last modified:April 17, 2007 - v1
Checksum:i72310EFF8A0E092C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000609 Genomic DNA Translation: ABO34997.1
RefSeqiWP_011868451.1, NC_009135.1

Genome annotation databases

EnsemblBacteriaiABO34997; ABO34997; MmarC5_0686
GeneIDi4928122
KEGGimmq:MmarC5_0686

Similar proteinsi

Entry informationi

Entry nameiRNP2_METM5
AccessioniPrimary (citable) accession number: A4FXR3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: March 28, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health