Reviewed, UniProtKB/Swiss-Prot A4FXR3 (RNP2_METM5)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 2
      Short name=RNase P component 2
    EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	MmarC5_0686

Organism

Methanococcus maripaludis (strain C5 / ATCC BAA-1333) [Complete proteome] [HAMAP]

Taxonomic identifier

402880 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	130 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 130	130	Ribonuclease P protein component 2 HAMAP MF_00755		PRO_1000046622

Sequences

	Sequence		Length	Mass (Da)
	A4FXR3-1 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 72310EFF8A0E092C	FASTA	130	15,270
	10 20 30 40 50 60 MLKTLPPTLR EKKRYVALEI IFEEELFQKD VIAIVRNALM NYSGVLGCSR TNPWLIDYNH 70 80 90 100 110 120 PYGILRISRE EVNNLRSSLS LTNEHRKKPI NIHIIGISNS VKHVREKFLH VPHEPYYKVI 130 QKLKKKGPKK

References

[1]

"Complete sequence of chromosome of Methanococcus maripaludis C5." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Detter J.C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000609 Genomic DNA. Translation: ABO34997.1.
RefSeq	YP_001097212.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4FXR3.
Genome annotation databases
GeneID	4928122.
GenomeReviews	Gene locus MmarC5_0686 in contig CP000609_GR.
KEGG	mmq:MmarC5_0686.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	LKTLPPT.
Family and domain databases
HAMAP	MF_00755. [Tree]
InterPro	IPR016434. RNase_P_comp-2. IPR002759. RNase_P_related. [Graphical view]
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
PIRSF	PIRSF004952. RNase_P_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP2_METM5

Accession

Primary (citable) accession number: A4FXR3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 17, 2007
Last modified:	November 3, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)