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A4FXH5

- TRPF_METM5

UniProt

A4FXH5 - TRPF_METM5

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene
trpF, MmarC5_0590
Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciMMAR402880:GJ2R-602-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:MmarC5_0590
OrganismiMethanococcus maripaludis (strain C5 / ATCC BAA-1333)
Taxonomic identifieri402880 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
ProteomesiUP000000253: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 208208N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotationPRO_1000057877Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi402880.MmarC5_0590.

Structurei

3D structure databases

ProteinModelPortaliA4FXH5.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiHDHRISQ.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

A4FXH5-1 [UniParc]FASTAAdd to Basket

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MFIKICGIKT PEELEIVENY GNATGVILEC VSKRRIGFET AKNLVNLANI    50
PVFAVSTTSD VSVWENIIEL TGTNYLQMHS DIDQKAIDFI KNEYGCFIMK 100
SFKIPEKSES PENDAQKIIS DIESYEVDRI LLDTGKGCGQ THDHRISQIL 150
AKKFDIVLAG GLDPDNVLKI VKTVKPFGVD VSSGVENNNS KDEELIKRFC 200
ENVKSVKL 208
Length:208
Mass (Da):23,202
Last modified:April 17, 2007 - v1
Checksum:i210F536864339129
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000609 Genomic DNA. Translation: ABO34904.1.
RefSeqiWP_011868358.1. NC_009135.1.
YP_001097119.1. NC_009135.1.

Genome annotation databases

EnsemblBacteriaiABO34904; ABO34904; MmarC5_0590.
GeneIDi4929305.
KEGGimmq:MmarC5_0590.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000609 Genomic DNA. Translation: ABO34904.1 .
RefSeqi WP_011868358.1. NC_009135.1.
YP_001097119.1. NC_009135.1.

3D structure databases

ProteinModelPortali A4FXH5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 402880.MmarC5_0590.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABO34904 ; ABO34904 ; MmarC5_0590 .
GeneIDi 4929305.
KEGGi mmq:MmarC5_0590.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi HDHRISQ.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci MMAR402880:GJ2R-602-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C5 / ATCC BAA-1333.

Entry informationi

Entry nameiTRPF_METM5
AccessioniPrimary (citable) accession number: A4FXH5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: April 17, 2007
Last modified: September 3, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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