A4FWY7 (RPIA_METM5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	MmarC5_0401

Organism

Methanococcus maripaludis (strain C5 / ATCC BAA-1333) [Complete proteome] [HAMAP]

Taxonomic identifier

402880 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	239 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 239	239	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_1000016948

Sequences

	Sequence		Length	Mass (Da)
	A4FWY7 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 62E7FC9389737A4E	FASTA	239	25,565
	10 20 30 40 50 60 MARTKKANDE VPTNSDSLKL KVAKQAAKLV KDEMVVGLGS GSTANLFIQE LGKRIVEEEL 70 80 90 100 110 120 YIYGVPTSFD SRMVASTAGI PLISLDQCGE IDIAVDGADE VCKSTLSLIK GGGGCHTMEK 130 140 150 160 170 180 IVDYHAKEFI VLADEGKLVD SLGDKTPVPL EVIPFAYSTV LNKLLKMNTA PAIRTGSGKM 190 200 210 220 230 GPVITDSGNM IIDVFISIDD AEETENMLNN IPGVLENGVF SKCDKVLVGT SKKVEILKK

References

[1]

"Complete sequence of chromosome of Methanococcus maripaludis C5." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Detter J.C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C5 / ATCC BAA-1333.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000609 Genomic DNA. Translation: ABO34716.1.
RefSeq	YP_001096931.1. NC_009135.1.
3D structure databases
ProteinModelPortal	A4FWY7.
SMR	A4FWY7. Positions 14-239.
ModBase	Search...
Protein-protein interaction databases
STRING	A4FWY7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4927896.
GenomeReviews	Gene locus MmarC5_0401 in contig CP000609_GR.
KEGG	mmq:MmarC5_0401.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG07879.
HOGENOM	HBG515603.
OMA	GGDPEYR.
PhylomeDB	A4FWY7.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	MMAR402880:MMARC5_0401-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. IPR014036. Tscrpt_reg_HTH_DeoR. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF00455. DeoR. 1 hit. PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_METM5

Accession

Primary (citable) accession number: A4FWY7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 17, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program