Reviewed, UniProtKB/Swiss-Prot A4FW85 (APGM_METM5)

Names and origin

Protein names

Recommended name:
    2,3-bisphosphoglycerate-independent phosphoglycerate mutase
      Short name=Phosphoglyceromutase
      Short name=BPG-independent PGAM
      Short name=aPGAM
    EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	MmarC5_0139

Organism

Methanococcus maripaludis (strain C5 / ATCC BAA-1333) [Complete proteome] [HAMAP]

Taxonomic identifier

402880 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	406 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 406	406	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402		PRO_1000087363

Sequences

	Sequence		Length	Mass (Da)
	A4FW85-1 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 186097EBB46E221D	FASTA	406	44,470
	10 20 30 40 50 60 MKAVIFIMDG LGDRPNKDGN TPLKEAKTPV MDKMAKDGIC GLMNAVDVGV RPGSDTAHLA 70 80 90 100 110 120 ILGYDPYTTY TGRGPFEACG VGVTVKPGDI AFRCNFSSVN ENFIVTDRRA GRIEDTSELE 130 140 150 160 170 180 KELDGLKIDD IDIIFKESGG YRAALVLRGP GLSDKISDAD PKKEGKRVKE IHPLDNSKEA 190 200 210 220 230 240 KKTAEIVNKL LKIAYEKLDK HPVNEERRKQ NLPVANMIVP RGVGQVPEIM QFSEKTGLKG 250 260 270 280 290 300 ACIAGTGLIK GIAKMVGLDV IDVEGCDGTP NSDLMAKACA IVETLKDYDF ILVNVKGADE 310 320 330 340 350 360 AGHDGNYELK KEIIEKIDEM LDYITKNIDK DEVYIAMSGD HSTPIEEMDH SADPLPILIW 370 380 390 400 GKSVRVDDVE KFDEFSTYKG GLNWIKGTNI MPILMDLMSI AKKYGA

References

[1]

"Complete sequence of chromosome of Methanococcus maripaludis C5." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Detter J.C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000609 Genomic DNA. Translation: ABO34456.1.
RefSeq	YP_001096671.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4FW85.
Genome annotation databases
GeneID	4927786.
GenomeReviews	Gene locus MmarC5_0139 in contig CP000609_GR.
KEGG	mmq:MmarC5_0139.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ITGDHST.
Family and domain databases
HAMAP	MF_01402. [Tree]
InterPro	IPR004456. APGAM_arc. IPR019304. bisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
ProDom	PD004704. APGAM_DeoB. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00306. apgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_METM5

Accession

Primary (citable) accession number: A4FW85

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	April 17, 2007
Last modified:	November 3, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)