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A4FW85 (APGM_METM5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1
Gene names
Name:apgM
Ordered Locus Names:MmarC5_0139
OrganismMethanococcus maripaludis (strain C5 / ATCC BAA-1333) [Complete proteome] [HAMAP]
Taxonomic identifier402880 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length406 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A

Sequence similarities

Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
   Biological processGlycolysis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: InterPro

phosphoglycerate mutase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4064062,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A
PRO_1000087363

Sequences

Sequence LengthMass (Da)Tools
A4FW85 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: 186097EBB46E221D

FASTA40644,470
        10         20         30         40         50         60 
MKAVIFIMDG LGDRPNKDGN TPLKEAKTPV MDKMAKDGIC GLMNAVDVGV RPGSDTAHLA 

        70         80         90        100        110        120 
ILGYDPYTTY TGRGPFEACG VGVTVKPGDI AFRCNFSSVN ENFIVTDRRA GRIEDTSELE 

       130        140        150        160        170        180 
KELDGLKIDD IDIIFKESGG YRAALVLRGP GLSDKISDAD PKKEGKRVKE IHPLDNSKEA 

       190        200        210        220        230        240 
KKTAEIVNKL LKIAYEKLDK HPVNEERRKQ NLPVANMIVP RGVGQVPEIM QFSEKTGLKG 

       250        260        270        280        290        300 
ACIAGTGLIK GIAKMVGLDV IDVEGCDGTP NSDLMAKACA IVETLKDYDF ILVNVKGADE 

       310        320        330        340        350        360 
AGHDGNYELK KEIIEKIDEM LDYITKNIDK DEVYIAMSGD HSTPIEEMDH SADPLPILIW 

       370        380        390        400 
GKSVRVDDVE KFDEFSTYKG GLNWIKGTNI MPILMDLMSI AKKYGA

« Hide

References

[1]"Complete sequence of chromosome of Methanococcus maripaludis C5."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Detter J.C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Richardson P.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C5 / ATCC BAA-1333.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000609 Genomic DNA. Translation: ABO34456.1.
RefSeqYP_001096671.1. NC_009135.1.

3D structure databases

ProteinModelPortalA4FW85.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4FW85.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4927786.
GenomeReviewsGene locus MmarC5_0139 in contig CP000609_GR.
KEGGmmq:MmarC5_0139.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04733.
HOGENOMHBG463247.
OMADIAFRCN.
ProtClustDBPRK04024.

Enzyme and pathway databases

BioCycMMAR402880:MMARC5_0139-MONOMER.

Family and domain databases

HAMAPMF_01402_A. ApgM_A.
[Tree]
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR023665. ApgAM.
IPR004456. BisP-indep_Pglycerate_Mutase.
IPR006124. Metalloenzyme.
[Graphical view]
Gene3DG3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KOK15635.
PfamPF01676. Metalloenzyme. 1 hit.
PF10143. PhosphMutase. 1 hit.
[Graphical view]
PIRSFPIRSF006392. IPGAM_arch. 1 hit.
SUPFAMSSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMsTIGR00306. ApgM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPGM_METM5
AccessionPrimary (citable) accession number: A4FW85
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 17, 2007
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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