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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit A

Gene

gatA

Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei55Charge relay systemUniRule annotation1
Active sitei130Charge relay systemUniRule annotation1
Active sitei154Acyl-ester intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotation (EC:6.3.5.7UniRule annotation)
Short name:
Glu-ADT subunit AUniRule annotation
Gene namesi
Name:gatAUniRule annotation
Ordered Locus Names:MmarC5_0065
OrganismiMethanococcus maripaludis (strain C5 / ATCC BAA-1333)
Taxonomic identifieri402880 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000000253 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000158611 – 431Glutamyl-tRNA(Gln) amidotransferase subunit AAdd BLAST431

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Protein-protein interaction databases

STRINGi402880.MmarC5_0065.

Structurei

3D structure databases

ProteinModelPortaliA4FW11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amidase family. GatA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01717. Archaea.
COG0154. LUCA.
HOGENOMiHOG000116699.
KOiK02433.
OMAiKEYFGAG.

Family and domain databases

Gene3Di3.90.1300.10. 1 hit.
HAMAPiMF_00120. GatA. 1 hit.
InterProiIPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view]
PANTHERiPTHR11895. PTHR11895. 1 hit.
PfamiPF01425. Amidase. 1 hit.
[Graphical view]
SUPFAMiSSF75304. SSF75304. 1 hit.
TIGRFAMsiTIGR00132. gatA. 1 hit.
PROSITEiPS00571. AMIDASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4FW11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITDRVSDYL EKIEKSDVNA FIDVNSEKVL KEAEELEKND DLKNKPLYGK
60 70 80 90 100
IVAVKSNINV KGYKISCASK TLEKYVGTYD ATVVKKLRSQ GALIVGMTNM
110 120 130 140 150
DEFAGGSSGE TSCYGPTKNP AALDRIPGGS SSGSAAAVAA DLCDMAIGSD
160 170 180 190 200
TGGSIRNPAS HCGIVGFKPS YGVVSRQGLC DLAMSFDQIG PLTKNAEDAL
210 220 230 240 250
VLTNAIKGID RSDSTSLETP KFEKKDISNY KVGVVKEFMD VTDEKIRNEI
260 270 280 290 300
EKGIEVFKDM GCKIVDLSYK YIDLALPTYY LINYVEFFSA TRKYDGRRYG
310 320 330 340 350
EFIEEACGEE VLRRILIGKH ISEQEFSGKY YKKALQARKS MKKEMLGLFN
360 370 380 390 400
SADLIVGPTV PKLPHKLGED LSPMEMYAYD VLTVPTNICG ICSGVVRCGN
410 420 430
ISGVPVGLQI QGAPLEDEKV LSAMIEFEKN Y
Length:431
Mass (Da):47,165
Last modified:April 17, 2007 - v1
Checksum:i4FE7D94B15CF4ED3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000609 Genomic DNA. Translation: ABO34382.1.
RefSeqiWP_011867844.1. NC_009135.1.

Genome annotation databases

EnsemblBacteriaiABO34382; ABO34382; MmarC5_0065.
GeneIDi4927607.
KEGGimmq:MmarC5_0065.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000609 Genomic DNA. Translation: ABO34382.1.
RefSeqiWP_011867844.1. NC_009135.1.

3D structure databases

ProteinModelPortaliA4FW11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi402880.MmarC5_0065.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO34382; ABO34382; MmarC5_0065.
GeneIDi4927607.
KEGGimmq:MmarC5_0065.

Phylogenomic databases

eggNOGiarCOG01717. Archaea.
COG0154. LUCA.
HOGENOMiHOG000116699.
KOiK02433.
OMAiKEYFGAG.

Family and domain databases

Gene3Di3.90.1300.10. 1 hit.
HAMAPiMF_00120. GatA. 1 hit.
InterProiIPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view]
PANTHERiPTHR11895. PTHR11895. 1 hit.
PfamiPF01425. Amidase. 1 hit.
[Graphical view]
SUPFAMiSSF75304. SSF75304. 1 hit.
TIGRFAMsiTIGR00132. gatA. 1 hit.
PROSITEiPS00571. AMIDASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGATA_METM5
AccessioniPrimary (citable) accession number: A4FW11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: November 2, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.