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Protein
Submitted name:

eIF2C2 protein

Gene

EIF2C2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processRNA-mediated gene silencingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
eIF2C2 proteinImported
Gene namesi
Name:EIF2C2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27694

PTM / Processingi

Proteomic databases

PeptideAtlasiA4FVC0
PRIDEiA4FVC0

Expressioni

Gene expression databases

GenevisibleiA4FVC0 HS

Interactioni

Protein-protein interaction databases

IntActiA4FVC0 11 interactors.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini184 – 297PAZInterPro annotationAdd BLAST114
Domaini466 – 767PiwiInterPro annotationAdd BLAST302

Sequence similaritiesi

Belongs to the argonaute family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1041 Eukaryota
ENOG410XP07 LUCA
HOVERGENiHBG006101

Family and domain databases

Gene3Di3.30.420.101 hit
InterProiView protein in InterPro
IPR014811 ArgoL1
IPR032472 ArgoL2
IPR032473 Argonaute_Mid_dom
IPR032474 Argonaute_N
IPR003100 PAZ_dom
IPR036085 PAZ_dom_sf
IPR003165 Piwi
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PfamiView protein in Pfam
PF08699 ArgoL1, 1 hit
PF16488 ArgoL2, 1 hit
PF16487 ArgoMid, 1 hit
PF16486 ArgoN, 1 hit
PF02170 PAZ, 1 hit
PF02171 Piwi, 1 hit
SMARTiView protein in SMART
SM01163 DUF1785, 1 hit
SM00949 PAZ, 1 hit
SM00950 Piwi, 1 hit
SUPFAMiSSF101690 SSF101690, 1 hit
SSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50821 PAZ, 1 hit
PS50822 PIWI, 1 hit

Sequencei

Sequence statusi: Fragment.

A4FVC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RPPLGPGAPR RRHHVLGSRP REIVEHMVQH FKTQIFGDRK PVFDGRKNLY
60 70 80 90 100
TAMPLPIGRD KVELEVTLPG EGKDRIFKVS IKWVSCVSLQ ALHDALSGRL
110 120 130 140 150
PSVPFETIQA LDVVMRHLPS MRYTPVGRSF FTASEGCSNP LGGGREVWFG
160 170 180 190 200
FHQSVRPSLW KMMLNIDVSA TAFYKAQPVI EFVCEVLDFK SIEEQQKPLT
210 220 230 240 250
DSQRVKFTKE IKGLKVEITH CGQMKRKYRV CNVTRRPASH QTFPLQQESG
260 270 280 290 300
QTVECTVAQY FKDRHKLVLR YPHLPCLQVG QEQKHTYLPL EVCNIVAGQR
310 320 330 340 350
CIKKLTDNQT STMIRATARS APDRQEEISK LMRSASFNTD PYVREFGIMV
360 370 380 390 400
KDEMTDVTGR VLQPPSILYG GRNKAIATPV QGVWDMRNKQ FHTGIEIKVW
410 420 430 440 450
AIACFAPQRQ CTEVHLKSFT EQLRKISRDA GMPIQGQPCF CKYAQGADSV
460 470 480 490 500
EPMFRHLKNT YAGLQLVVVI LPGKTPVYAE VKRVGDTVLG MATQCVQMKN
510 520 530 540 550
VQRTTPQTLS NLCLKINVKL GGVNNILLPQ GRPPVFQQPV IFLGADVTHP
560 570 580 590 600
PAGDGKKPSI AAVVGSMDAH PNRYCATVRV QQHRQEIIQD LAAMVRELLI
610 620 630 640 650
QFYKSTRFKP TRIIFYRDGV SEGQFQQVLH HELLAIREAC IKLEKDYQPG
660 670 680 690 700
ITFIVVQKRH HTRLFCTDKN ERVGKSGNIP AGTTVDTKIT HPTEFDFYLC
710 720 730 740 750
SHAGIQGTSR PSHYHVLWDD NRFSSDELQI LTYQLCHTYV RCTRSVSIPA
760 770 780 790 800
PAYYAHLVAF RARYHLVDKE HDSAEGSHTS GQSNGRDHQA LAKAVQVHQD

TLRTMYFA
Length:808
Mass (Da):91,497
Last modified:April 17, 2007 - v1
Checksum:i7D58FD57997FAC7D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125213 mRNA Translation: AAI25214.1
UniGeneiHs.660189
Hs.743313

Similar proteinsi

Entry informationi

Entry nameiA4FVC0_HUMAN
AccessioniPrimary (citable) accession number: A4FVC0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: February 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.