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Protein
Submitted name:

NRXN1 protein

Gene

NRXN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
NRXN1 proteinImported
Gene namesi
Name:NRXN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei322 – 342HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31786.

PTM / Processingi

Proteomic databases

PRIDEiA4FVB9.

Expressioni

Gene expression databases

GenevisibleiA4FVB9. HS.

Structurei

3D structure databases

ProteinModelPortaliA4FVB9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 213LAM_G_DOMAINInterPro annotationAdd BLAST169

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG052670.
KOiK07377.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR001791. Laminin_G.
IPR029824. Neurexin-1.
IPR003585. Neurexin-like.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF565. PTHR10127:SF565. 2 hits.
PfamiPF02210. Laminin_G_2. 1 hit.
PF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A4FVB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ALEIWEQPPA PRLLFPGLPF RTSPSPAAIY RSPASLRGGH AGTTYIFSKG
60 70 80 90 100
GGQITYKWPP NDRPSTRADR LAIGFSTVQK EAVLVRVDSS SGLGDYLELH
110 120 130 140 150
IHQGKIGVKF NVGTDDIAIE ESNAIINDGK YHVVRFTRSG GNATLQVDSW
160 170 180 190 200
PVIERYPAGR QLTIFNSQAT IIIGGKEQGQ PFQGQLSGLY YNGLKVLNMA
210 220 230 240 250
AENDANIAIV GNVRLVGEVP SSMTTESTAT AMQSEMSTSI METTTTLATS
260 270 280 290 300
TARRGKPPTK EPISQTTDDI LVASAECPSD DEDIDPCEPS SGGLANPTRA
310 320 330 340 350
GGREPYPGSA EVIRESSSTT GMVVGIVAAA ALCILILLYA MYKYRNRDEG
360 370 380 390
SYHVDESRNY ISNSAQSNGA VVKEKQPSSA KSSNKNKKNK DKEYYV
Length:396
Mass (Da):42,631
Last modified:April 17, 2007 - v1
Checksum:i77097C072F45592D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125179 mRNA. Translation: AAI25180.1.
UniGeneiHs.637685.

Genome annotation databases

KEGGihsa:9378.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125179 mRNA. Translation: AAI25180.1.
UniGeneiHs.637685.

3D structure databases

ProteinModelPortaliA4FVB9.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA4FVB9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGihsa:9378.

Organism-specific databases

CTDi9378.
PharmGKBiPA31786.

Phylogenomic databases

HOVERGENiHBG052670.
KOiK07377.

Miscellaneous databases

ChiTaRSiNRXN1. human.
GenomeRNAii9378.

Gene expression databases

GenevisibleiA4FVB9. HS.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR001791. Laminin_G.
IPR029824. Neurexin-1.
IPR003585. Neurexin-like.
IPR027789. Syndecan/Neurexin_dom.
[Graphical view]
PANTHERiPTHR10127:SF565. PTHR10127:SF565. 2 hits.
PfamiPF02210. Laminin_G_2. 1 hit.
PF01034. Syndecan. 1 hit.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
SM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS50025. LAM_G_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA4FVB9_HUMAN
AccessioniPrimary (citable) accession number: A4FVB9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: November 2, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.