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A4FUZ5 (SERC3_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine incorporator 3
Gene names
Name:SERINC3
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length472 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in cellular transformation By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein By similarity.

Post-translational modification

N-glycosylated By similarity.

Sequence similarities

Belongs to the TDE1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 472472Serine incorporator 3
PRO_0000342158

Regions

Topological domain1 – 9595Extracellular Potential
Transmembrane96 – 11621Helical; Potential
Topological domain117 – 13115Cytoplasmic Potential
Transmembrane132 – 15221Helical; Potential
Topological domain153 – 1586Extracellular Potential
Transmembrane159 – 17921Helical; Potential
Topological domain180 – 20223Cytoplasmic Potential
Transmembrane203 – 22321Helical; Potential
Topological domain224 – 23815Extracellular Potential
Transmembrane239 – 25921Helical; Potential
Topological domain260 – 32869Cytoplasmic Potential
Transmembrane329 – 34921Helical; Potential
Topological domain350 – 40556Extracellular Potential
Transmembrane406 – 42621Helical; Potential
Topological domain427 – 44519Cytoplasmic Potential
Transmembrane446 – 46621Helical; Potential
Topological domain467 – 4726Extracellular Potential

Amino acid modifications

Modified residue3701Phosphoserine By similarity
Glycosylation341N-linked (GlcNAc...) Potential
Glycosylation3541N-linked (GlcNAc...) Potential
Glycosylation4031N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A4FUZ5 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: C32AF14F63A6EEA1

FASTA47252,418
        10         20         30         40         50         60 
MGAVLGVFSL ASWVPCLCGG ASCLLCSCCP NSKNSTLTRL IYAFILFLGT IVCCIMFHEG 

        70         80         90        100        110        120 
METQLKKIPG FCDEGLSTRI TDIMDKECDV LVRYKAVYRI SFALAVFFFA FSLLMLNVKT 

       130        140        150        160        170        180 
SKDPRAAIHN GFWFFKIAAI VGVMVGSFYI PGGHFNTAWF VIGMVGAAFF ILIQLVLLVD 

       190        200        210        220        230        240 
FAHSWNESWV NRMEEGNPKC WYAALLSVTS LFYILSIIFA GLLYTYYTKP DGCTENKFFI 

       250        260        270        280        290        300 
SFNLILCVVI SVLSIHPKIQ EHQPRSGLLQ SSLITLYTMY LTWSAMSNEP DRSCNPGLLS 

       310        320        330        340        350        360 
IITHMTSSTL APANTTAPAP TPAVPLQSGP SLNKENFIGL LVFVLSLSYS SIRNSSNSQV 

       370        380        390        400        410        420 
SKLTLSGSDS VILRDTAANG ASDEEDGRPR RAVDNEREGV QYNYSMFHLM LCSASLYIMM 

       430        440        450        460        470 
TLTNWYSPDA NFQSMTSKWP AVWVKISSSW VCLLLYVWTL VAPLVLTNRD FS

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Hereford.
Tissue: Basal ganglia.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC123501 mRNA. Translation: AAI23502.1.
IPIIPI00713989.
RefSeqNP_001076881.1. NM_001083412.1.
UniGeneBt.40520.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING9913.ENSBTAP00000002833.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSBTAT00000002833; ENSBTAP00000002833; ENSBTAG00000002187.
GeneID511861.
KEGGbta:511861.

Organism-specific databases

CTD10955.

Phylogenomic databases

eggNOGNOG308011.
GeneTreeENSGT00550000074522.
HOGENOMHOG000165463.
HOVERGENHBG025699.
InParanoidA4FUZ5.
OMACCPNSKN.
OrthoDBEOG4S4PGF.

Family and domain databases

InterProIPR005016. TMS_TDE.
[Graphical view]
PANTHERPTHR10383. PTHR10383. 1 hit.
PfamPF03348. Serinc. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20870133.

Entry information

Entry nameSERC3_BOVIN
AccessionPrimary (citable) accession number: A4FUZ5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: April 17, 2007
Last modified: April 3, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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