A4FUW1 (A4FUW1_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
4932417H02Rik protein EMBL AAI18972.1

Gene names

Name:	Rptor MGI 1921620
Synonyms:	4932417H02Rik EMBL AAI18972.1

Organism

Mus musculus (Mouse) EMBL AAI18972.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1333 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Repeat RuleBase RU003532 WD repeat RuleBase RU000362
Gene Ontology (GO)
Biological_process	TOR signaling Inferred from electronic annotation. Source: Ensembl cell growth Inferred from electronic annotation. Source: Ensembl cellular response to amino acid stimulus Inferred from electronic annotation. Source: Ensembl cellular response to nutrient levels Inferred from electronic annotation. Source: Ensembl positive regulation of TOR signaling Inferred from electronic annotation. Source: Ensembl positive regulation of endothelial cell proliferation Inferred from electronic annotation. Source: Ensembl positive regulation of protein serine/threonine kinase activity Inferred from electronic annotation. Source: Ensembl positive regulation of transcription from RNA polymerase III promoter Inferred from electronic annotation. Source: Ensembl regulation of cell size Inferred from electronic annotation. Source: Ensembl
Cellular_component	TORC1 complex Inferred from sequence orthology PubMed 15467718. Source: MGI lysosome Inferred from electronic annotation. Source: Ensembl
Molecular_function	RNA polymerase III type 1 promoter DNA binding Inferred from electronic annotation. Source: Ensembl RNA polymerase III type 2 promoter DNA binding Inferred from electronic annotation. Source: Ensembl RNA polymerase III type 3 promoter DNA binding Inferred from electronic annotation. Source: Ensembl
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAI18972.1

Sequences

	Sequence		Length	Mass (Da)
	A4FUW1 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 60A3334526AB9085	FASTA	1,333	149,237
	10 20 30 40 50 60 SEMLQSPLMG LGEEDEADLT DWNLPLAFMK KRHCEKIEGS KSLAQSWRMK DRMKTVSVAL 70 80 90 100 110 120 VLCLNVGVDP PDVVKTTPCA RLECWIDPLS MGPQKALETI GANLQKQYEN WQPRARYKQS 130 140 150 160 170 180 LDPTVDEVKK LCTSLRRNAK EERVLFHYNG HGVPRPTVNG EVWVFNKNYT QYIPLSIYDL 190 200 210 220 230 240 QTWMGSPSIF VYDCSNAGLI VKSFKQFALQ REQELEVAAI NPNHPLAQMP LPPSMKNCIQ 250 260 270 280 290 300 LAACEAHELL PMIPDLPADL FTSCLTTPIK IALRWFCMQK CVSLVPGVTL DLIEKIPGRL 310 320 330 340 350 360 NDRRTPLGEL NWIFTAITDT IAWNVLPRDL FQKLFRQDLL VASLFRNFLL AERIMRSYNC 370 380 390 400 410 420 TPVSSPRLPP TYMHAMWQAW DLAVDICLSQ LPTIIEEGTA FRHSPFFAEQ LTAFQVWLTM 430 440 450 460 470 480 GVENRSPPEQ LPIVLQVLLS QVHRLRALDL LGRFLDLGPW AVSLALSVGI FPYVLKLLQS 490 500 510 520 530 540 SARELRPLLV FIWAKILAVD SSCQADLVKD NGHKYFLSVL ADPYMPAEHR TMTAFILAVI 550 560 570 580 590 600 VNSYTTGQEA CLQGNLIAIC LEQLSDPHPL LRQWVAICLG RIWQNFDSAR WCGVRDSAHE 610 620 630 640 650 660 KLYSLLSDPI PEVRCAAVFA LGTFVGNSAE RTDHSTTIDH NVAMMLAQLI NDGSPMVRKE 670 680 690 700 710 720 LVVALSHLVV QYESNFCTVA LQFMEEEKNY PLPSPAATEG GSLTPVRDSP CTPRLRSVSS 730 740 750 760 770 780 YGNIRAVTTA RNLNKSLQNL SLTEESGSSV AFSPGNLSTS SSASSTLGSP ENEEYILSFE 790 800 810 820 830 840 TIDKMRRVSS YSALNSLIGV SFNSVYTQIW RVLLHLAADP YPDVSDLAMK VLNSIAYKAT 850 860 870 880 890 900 VNARPQRILD TSSLTQSAPA SPTNKGMHMH QVGGSPPASS TSSCSLTNDV AKQTVSRDLP 910 920 930 940 950 960 SSRPGTAGPT GAQYTPHSHQ FPRTRKMFDK GPDQTTDDAD DAAGHKSFIC ASMQTGFCDW 970 980 990 1000 1010 1020 SARYFAQPVM KIPEEHDLES QIRKEREWRF LRNTRVRKQA QQVIQKGITR LDDQIFLNRN 1030 1040 1050 1060 1070 1080 PGVPSVVKFH PFTPCIAVAD KDSICFWDWE KGEKLDYFHN GNPRYTRVTA MEYLNGQDCS 1090 1100 1110 1120 1130 1140 LLLTATDDGA IRVWKNFADL EKNPEMVTAW QGLSDMLPTT RGAGMVVDWE QETGLLMSSG 1150 1160 1170 1180 1190 1200 DVRIVRIWDT DRETKVQDIP TGADSCVTSL SCDSHRSLIV AGLGDGSIRV YDRRMALSEC 1210 1220 1230 1240 1250 1260 RVMTYREHTA WVVKAYLQKH PEGHIVSVSV NGDVRFFDPR MPESVNVMQI VKGLTALDIH 1270 1280 1290 1300 1310 1320 PQANLIACGS MNQFTAIYNG NGELINNIKY YDGFMGQRVG AISCLAFHPH WPHLAVGSND 1330 YYISVYSVEK RVR

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI18972.1.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC118971 mRNA. Translation: AAI18972.1.
RefSeq	NP_083174.2. NM_028898.2.
UniGene	Mm.209933.
3D structure databases
ProteinModelPortal	A4FUW1.
ModBase	Search...
MobiDB	Search...
Proteomic databases
PRIDE	A4FUW1.
Protocols and materials databases
DNASU	74370.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	74370.
KEGG	mmu:74370.
UCSC	uc011yit.1. mouse.
Organism-specific databases
CTD	57521.
MGI	MGI:1921620. Rptor.
Phylogenomic databases
HOVERGEN	HBG059496.
InParanoid	A4FUW1.
KO	K07204.
Gene expression databases
Bgee	A4FUW1.
Genevestigator	A4FUW1.
Family and domain databases
Gene3D	1.25.10.10. 2 hits. 2.130.10.10. 3 hits.
InterPro	IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR004083. Raptor. IPR027466. Raptor_metazoan. IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR017986. WD40_repeat_dom. [Graphical view]
PANTHER	PTHR12848. PTHR12848. 1 hit. PTHR12848:SF6. PTHR12848:SF6. 1 hit.
Pfam	PF00400. WD40. 2 hits. [Graphical view]
PRINTS	PR01547. YEAST176DUF.
SMART	SM00320. WD40. 7 hits. [Graphical view]
SUPFAM	SSF48371. SSF48371. 2 hits. SSF50978. SSF50978. 1 hit.
PROSITE	PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	RPTOR. mouse.
NextBio	340575.
SOURCE	Search...

Entry information

Entry name

A4FUW1_MOUSE

Accession

Primary (citable) accession number: A4FUW1

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	April 16, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)