Rptor

Functionⁱ

GO - Biological processⁱ

TOR signaling Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: 4932417H02Rik proteinImported
Gene namesⁱ	Name:RptorImported Synonyms:4932417H02RikImported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:1921620. Rptor.

Subcellular locationⁱ

GO - Cellular componentⁱ

TORC1 complex Source: InterPro

Complete GO annotation...

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	A4FUW1.

PaxDbⁱ

A4FUW1.

Expressionⁱ

Gene expression databases

Genevisibleⁱ	A4FUW1. MM.

Genevisibleⁱ

A4FUW1. MM.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A4FUW1.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1117 – 1247	WD_REPEATS_REGIONInterPro annotationAdd BLAST		131

Keywords - Domainⁱ

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1517. Eukaryota. ENOG410XQKJ. LUCA.
HOVERGENⁱ	HBG059496.

Family and domain databases

Gene3Dⁱ	1.25.10.10. 2 hits. 2.130.10.10. 2 hits.
InterProⁱ	View protein in InterPro IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR000357. HEAT. IPR004083. Raptor. IPR029347. Raptor_N. IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR017986. WD40_repeat_dom.
PANTHERⁱ	PTHR12848. PTHR12848. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02985. HEAT. 1 hit. PF14538. Raptor_N. 1 hit. PF00400. WD40. 1 hit.
SMARTⁱ	View protein in SMART SM01302. Raptor_N. 1 hit. SM00320. WD40. 7 hits.
SUPFAMⁱ	SSF48371. SSF48371. 2 hits. SSF50978. SSF50978. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50294. WD_REPEATS_REGION. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

A4FUW1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
SEMLQSPLMG LGEEDEADLT DWNLPLAFMK KRHCEKIEGS KSLAQSWRMK 
        60         70         80         90        100
DRMKTVSVAL VLCLNVGVDP PDVVKTTPCA RLECWIDPLS MGPQKALETI 
       110        120        130        140        150
GANLQKQYEN WQPRARYKQS LDPTVDEVKK LCTSLRRNAK EERVLFHYNG 
       160        170        180        190        200
HGVPRPTVNG EVWVFNKNYT QYIPLSIYDL QTWMGSPSIF VYDCSNAGLI 
       210        220        230        240        250
VKSFKQFALQ REQELEVAAI NPNHPLAQMP LPPSMKNCIQ LAACEAHELL 
       260        270        280        290        300
PMIPDLPADL FTSCLTTPIK IALRWFCMQK CVSLVPGVTL DLIEKIPGRL 
       310        320        330        340        350
NDRRTPLGEL NWIFTAITDT IAWNVLPRDL FQKLFRQDLL VASLFRNFLL 
       360        370        380        390        400
AERIMRSYNC TPVSSPRLPP TYMHAMWQAW DLAVDICLSQ LPTIIEEGTA 
       410        420        430        440        450
FRHSPFFAEQ LTAFQVWLTM GVENRSPPEQ LPIVLQVLLS QVHRLRALDL 
       460        470        480        490        500
LGRFLDLGPW AVSLALSVGI FPYVLKLLQS SARELRPLLV FIWAKILAVD 
       510        520        530        540        550
SSCQADLVKD NGHKYFLSVL ADPYMPAEHR TMTAFILAVI VNSYTTGQEA 
       560        570        580        590        600
CLQGNLIAIC LEQLSDPHPL LRQWVAICLG RIWQNFDSAR WCGVRDSAHE 
       610        620        630        640        650
KLYSLLSDPI PEVRCAAVFA LGTFVGNSAE RTDHSTTIDH NVAMMLAQLI 
       660        670        680        690        700
NDGSPMVRKE LVVALSHLVV QYESNFCTVA LQFMEEEKNY PLPSPAATEG 
       710        720        730        740        750
GSLTPVRDSP CTPRLRSVSS YGNIRAVTTA RNLNKSLQNL SLTEESGSSV 
       760        770        780        790        800
AFSPGNLSTS SSASSTLGSP ENEEYILSFE TIDKMRRVSS YSALNSLIGV 
       810        820        830        840        850
SFNSVYTQIW RVLLHLAADP YPDVSDLAMK VLNSIAYKAT VNARPQRILD 
       860        870        880        890        900
TSSLTQSAPA SPTNKGMHMH QVGGSPPASS TSSCSLTNDV AKQTVSRDLP 
       910        920        930        940        950
SSRPGTAGPT GAQYTPHSHQ FPRTRKMFDK GPDQTTDDAD DAAGHKSFIC 
       960        970        980        990       1000
ASMQTGFCDW SARYFAQPVM KIPEEHDLES QIRKEREWRF LRNTRVRKQA 
      1010       1020       1030       1040       1050
QQVIQKGITR LDDQIFLNRN PGVPSVVKFH PFTPCIAVAD KDSICFWDWE 
      1060       1070       1080       1090       1100
KGEKLDYFHN GNPRYTRVTA MEYLNGQDCS LLLTATDDGA IRVWKNFADL 
      1110       1120       1130       1140       1150
EKNPEMVTAW QGLSDMLPTT RGAGMVVDWE QETGLLMSSG DVRIVRIWDT 
      1160       1170       1180       1190       1200
DRETKVQDIP TGADSCVTSL SCDSHRSLIV AGLGDGSIRV YDRRMALSEC 
      1210       1220       1230       1240       1250
RVMTYREHTA WVVKAYLQKH PEGHIVSVSV NGDVRFFDPR MPESVNVMQI 
      1260       1270       1280       1290       1300
VKGLTALDIH PQANLIACGS MNQFTAIYNG NGELINNIKY YDGFMGQRVG 
      1310       1320       1330 
AISCLAFHPH WPHLAVGSND YYISVYSVEK RVR

Length:1,333

Mass (Da):149,237

Last modified:April 17, 2007 - v1

Checksum:ⁱ60A3334526AB9085

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC118971 mRNA. Translation: AAI18972.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_083174.2. NM_028898.3.
UniGeneⁱ	Mm.209933. Mm.442144. Mm.450470. Mm.462932.

Genome annotation databases

GeneIDⁱ	74370.
UCSC genome browser More...UCSCⁱ	uc011yit.1. mouse.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
A4FUW1	A2ACM0 Q6ZPU3 UPI0005ABA193 UPI0003D7285B UPI0000214733	Mus musculus (Mouse)	1,335	UniRef100_A2ACM0	Cluster: Putative uncharacterized protein	6

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
A4FUW1	Q8K4Q0 Q8K4Q0-5 UPI0005FC16C7 UPI000952FA20 UPI000A1B995A UPI0004404680 UPI000717C56E UPI0007194B79 UPI00042D0D55 UPI000577B3A9 +164	Mus musculus (Mouse) Ovis aries musimon (Mouflon) Bos indicus (Zebu) Odocoileus virginianus texanus Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni) Equus caballus (Horse) Ceratotherium simum simum (southern white rhinoceros) Bubalus bubalis (Domestic water buffalo) Bison bison bison Equus asinus (Donkey) (Equus africanus asinus) And more	1,335	UniRef90_Q8K4Q0	Cluster: Regulatory-associated protein of mTOR	175

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
A4FUW1	Q8K4Q0 Q8K4Q0-5 UPI000A1B995A UPI000577B3A9 UPI00071A0FCB UPI000952FA20 UPI0004404680 UPI000717C56E UPI0003840FC9 UPI0005FC16C7 +324	Mus musculus (Mouse) Odocoileus virginianus texanus Bison bison bison Equus asinus (Donkey) (Equus africanus asinus) Bos indicus (Zebu) Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni) Equus caballus (Horse) Bos taurus (Bovine) Ovis aries musimon (Mouflon) Bubalus bubalis (Domestic water buffalo) And more	1,335	UniRef50_Q8K4Q0	Cluster: Regulatory-associated protein of mTOR	335

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC118971 mRNA. Translation: AAI18972.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_083174.2. NM_028898.3.
UniGeneⁱ	Mm.209933. Mm.442144. Mm.450470. Mm.462932.

3D structure databases

ProteinModelPortalⁱ	A4FUW1.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PaxDbⁱ	A4FUW1.

PaxDbⁱ

A4FUW1.

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	74370.
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	74370.
UCSC genome browser More...UCSCⁱ	uc011yit.1. mouse.

Organism-specific databases

CTDⁱ	57521.
MGIⁱ	MGI:1921620. Rptor.

Phylogenomic databases

eggNOGⁱ	KOG1517. Eukaryota. ENOG410XQKJ. LUCA.
HOVERGENⁱ	HBG059496.

Miscellaneous databases

ChiTaRSⁱ	Rptor. mouse.
SOURCEⁱ	Search...

Gene expression databases

Genevisibleⁱ	A4FUW1. MM.

Genevisibleⁱ

A4FUW1. MM.

Family and domain databases

Gene3Dⁱ	1.25.10.10. 2 hits. 2.130.10.10. 2 hits.
InterProⁱ	View protein in InterPro IPR011989. ARM-like. IPR016024. ARM-type_fold. IPR000357. HEAT. IPR004083. Raptor. IPR029347. Raptor_N. IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR017986. WD40_repeat_dom.
PANTHERⁱ	PTHR12848. PTHR12848. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02985. HEAT. 1 hit. PF14538. Raptor_N. 1 hit. PF00400. WD40. 1 hit.
SMARTⁱ	View protein in SMART SM01302. Raptor_N. 1 hit. SM00320. WD40. 7 hits.
SUPFAMⁱ	SSF48371. SSF48371. 2 hits. SSF50978. SSF50978. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50294. WD_REPEATS_REGION. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A4FUW1_MOUSE
Accessionⁱ	A4FUW1Primary (citable) accession number: A4FUW1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 17, 2007
	Last sequence update:	April 17, 2007
	Last modified:	August 30, 2017
	This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - A4FUW1 (A4FUW1_MOUSE)

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4932417H02Rik protein

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A4FUW1 (A4FUW1_MOUSE)

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4932417H02Rik protein

Rptor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ