Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

MKL1 protein

Gene

MKL1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
MKL1 proteinImported
Gene namesi
Name:MKL1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiA4FUJ8
PeptideAtlasiA4FUJ8
PRIDEiA4FUJ8

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA4FUJ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati24 – 49RPELPROSITE-ProRule annotationAdd BLAST26
Repeati68 – 93RPELPROSITE-ProRule annotationAdd BLAST26
Domaini347 – 381SAPInterPro annotationAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili56 – 76Sequence analysisAdd BLAST21
Coiled coili527 – 561Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IFJX Eukaryota
ENOG41101AM LUCA
HOVERGENiHBG036493
KOiK22525

Family and domain databases

Gene3Di1.10.720.30, 1 hit
InterProiView protein in InterPro
IPR029992 MRTF-A
IPR004018 RPEL_repeat
IPR003034 SAP_dom
IPR036361 SAP_dom_sf
PANTHERiPTHR22793:SF6 PTHR22793:SF6, 2 hits
PfamiView protein in Pfam
PF02755 RPEL, 2 hits
PF02037 SAP, 1 hit
SMARTiView protein in SMART
SM00707 RPEL, 2 hits
SM00513 SAP, 1 hit
SUPFAMiSSF68906 SSF68906, 1 hit
PROSITEiView protein in PROSITE
PS51073 RPEL, 2 hits
PS50800 SAP, 1 hit

Sequencei

Sequence statusi: Complete.

A4FUJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPLKSPAAF HEQRRSLERA RTEDYLKRKI RSRPERSELV RMHILEETSA
60 70 80 90 100
EPSLQAKQLK LKRARLADDL NEKIAQRPGP MELVEKNILP VESSLKEAII
110 120 130 140 150
VGQVNYPKVA DSSSFDEDSS DALSPEQPAS HESQGSVPSP LEARVSEPLL
160 170 180 190 200
SATSASPTQV VSQLPMGRDS REMLFLAEQP PLPPPPLLPP SLTNGTTIPT
210 220 230 240 250
AKSTPTLIKQ SQPKSASEKS QRSKKAKELK PKVKKLKYHQ YIPPDQKQDR
260 270 280 290 300
GAPPMDSSYA KILQQQQLFL QLQILNQQQQ QHHNYQAILP APPKSAGEAL
310 320 330 340 350
GSSGTPPVRS LSTTNSSSSS GAPGPCGLAR QNSTSLTGKP GALPANLDDM
360 370 380 390 400
KVAELKQELK LRSLPVSGTK TELIERLRAY QDQISPVPGA PKAPAATSIL
410 420 430 440 450
HKAGEVVVAF PAARLSTGPA LVAAGLAPAE VVVATVASSG VVKFGSTGST
460 470 480 490 500
PPVSPTPSER SLLSTGDENS TPGDTFGEMV TSPLTQLTLQ ASPLQILVKE
510 520 530 540 550
EGPRAGSCCL SPGGRAELEG RDKDQMLQEK DKQIEALTRM LRQKQQLVER
560 570 580 590 600
LKLQLEQEKR AQQPAPAPAP LGTPVKQENS FSSCQLSQQP LGPAHPFNPS
610 620 630 640 650
LAAPATNHID PCAVAPGPPS VVVKQEALQP EPEPVPAPQL LLGPQGPGLI
660 670 680 690 700
KGVAPPTLIT DSTGTHLVLT VTNKNADSPG LSSGSPQQPS SQPGSPAPAP
710 720 730 740 750
SAQMDLEHPL QPLFGTPTSL LKKEPPGYEE AMSQQPKQQE NGSSSQQMDD
760 770 780 790
LFDILIQSGG NPRNFSRFQG AAIPAREGEA IPEDSLWVPP GSTAITFC
Length:798
Mass (Da):85,046
Last modified:April 17, 2007 - v1
Checksum:i55B8CF6F845F873C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC115039 mRNA Translation: AAI15040.1
RefSeqiNP_001269589.1, NM_001282660.1
NP_001269590.1, NM_001282661.1
NP_001269591.1, NM_001282662.1
NP_001305068.1, NM_001318139.1
NP_065882.1, NM_020831.4
UniGeneiHs.654688

Genome annotation databases

GeneIDi57591
KEGGihsa:57591

Similar proteinsi

Entry informationi

Entry nameiA4FUJ8_HUMAN
AccessioniPrimary (citable) accession number: A4FUJ8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health