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Protein
Submitted name:

ANTXR2 protein

Gene

ANTXR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi10Divalent metal cationUniRule annotation1
Metal bindingi12Divalent metal cationUniRule annotation1
Metal bindingi76Divalent metal cationUniRule annotation1

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
ANTXR2 proteinImported
Gene namesi
Name:ANTXR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei277 – 299HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiA4FUA5.
PeptideAtlasiA4FUA5.
PRIDEiA4FUA5.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000306185.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 171VWFAInterPro annotationAdd BLAST170

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK1W. Eukaryota.
ENOG410YC57. LUCA.
HOVERGENiHBG050514.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR017360. Anthrax_toxin_rcpt.
IPR008399. Anthrax_toxin_rcpt_C.
IPR008400. Anthrax_toxin_rcpt_extracel.
IPR002035. VWF_A.
[Graphical view]
PfamiPF05586. Ant_C. 1 hit.
PF05587. Anth_Ig. 1 hit.
PF00092. VWA. 1 hit.
[Graphical view]
PIRSFiPIRSF038023. Anthrax_toxin_receptor_2. 1 hit.
ProDomiPD377005. Anthrax_toxin_rcpt_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
PROSITEiPS50234. VWFA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A4FUA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LPLSLPVSWS GSVANNWIEI YNFVQQLAER FVSPEMRLSF IVFSSQATII
60 70 80 90 100
LPLTGDRGKI SKGLEDLKRV SPVGETYIHE GLKLANEQIQ KAGGLKTSSI
110 120 130 140 150
IIALTDGKLD GLVPSYAEKE AKISRSLGAS VYCVGVLDFE QAQLERIADS
160 170 180 190 200
KEQVFPVKGG FQALKGIINS ILAQSCTEIL ELQPSSVCVG EEFQIVLSGR
210 220 230 240 250
GFMLGSRNGS VLCTYTVNET YTTSVKPVSV QLNSMLCPAP ILNKAGETLD
260 270 280 290 300
VSVSFNGGKS VISGSLIVTA TECSNGIAAI IVILVLLLLL GIGLMWWFWP
310 320 330 340 350
LCCKVVIKDP PPPPPPAPKE EEEEPLPTKK WPTVDASYYG GRGVGGIKRM
360 370 380 390 400
EVRWGDKGST EEGARLEKAK NAVVKIPEET EEPIRPRPPR PKPTHQPPQT
410 420 430 440
KWYTPIKGRL DALWALLRRQ YDRVSLMRPQ EGDEGRCINF SRVPSQ
Length:446
Mass (Da):48,841
Last modified:April 17, 2007 - v1
Checksum:i9D5B35F25DAFC38E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC114374 mRNA. Translation: AAI14375.1.
RefSeqiNP_001273710.1. NM_001286781.1.
UniGeneiHs.162963.

Genome annotation databases

GeneIDi118429.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC114374 mRNA. Translation: AAI14375.1.
RefSeqiNP_001273710.1. NM_001286781.1.
UniGeneiHs.162963.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000306185.

Proteomic databases

PaxDbiA4FUA5.
PeptideAtlasiA4FUA5.
PRIDEiA4FUA5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi118429.

Organism-specific databases

CTDi118429.

Phylogenomic databases

eggNOGiENOG410IK1W. Eukaryota.
ENOG410YC57. LUCA.
HOVERGENiHBG050514.

Miscellaneous databases

ChiTaRSiANTXR2. human.
GenomeRNAii118429.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR017360. Anthrax_toxin_rcpt.
IPR008399. Anthrax_toxin_rcpt_C.
IPR008400. Anthrax_toxin_rcpt_extracel.
IPR002035. VWF_A.
[Graphical view]
PfamiPF05586. Ant_C. 1 hit.
PF05587. Anth_Ig. 1 hit.
PF00092. VWA. 1 hit.
[Graphical view]
PIRSFiPIRSF038023. Anthrax_toxin_receptor_2. 1 hit.
ProDomiPD377005. Anthrax_toxin_rcpt_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
PROSITEiPS50234. VWFA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA4FUA5_HUMAN
AccessioniPrimary (citable) accession number: A4FUA5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: October 5, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.