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A4FPJ3

- RS4_SACEN

UniProt

A4FPJ3 - RS4_SACEN

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Protein

30S ribosomal protein S4

Gene

rpsD

Organism
Saccharopolyspora erythraea (strain NRRL 23338)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.UniRule annotation
With S5 and S12 plays an important role in translational accuracy.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S4UniRule annotation
Gene namesi
Name:rpsDUniRule annotation
Ordered Locus Names:SACE_6804
OrganismiSaccharopolyspora erythraea (strain NRRL 23338)
Taxonomic identifieri405948 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeSaccharopolyspora
ProteomesiUP000006728: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. small ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 20120130S ribosomal protein S4PRO_0000293360Add
BLAST

Proteomic databases

PRIDEiA4FPJ3.

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.UniRule annotation

Protein-protein interaction databases

STRINGi405948.SACE_6804.

Structurei

3D structure databases

ProteinModelPortaliA4FPJ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini91 – 15767S4 RNA-bindingUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ribosomal protein S4P family.UniRule annotation
Contains 1 S4 RNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0522.
HOGENOMiHOG000221004.
KOiK02986.
OMAiTCKLSRR.
OrthoDBiEOG6N3CXM.

Family and domain databases

Gene3Di1.10.1050.10. 1 hit.
3.10.290.10. 1 hit.
HAMAPiMF_01306_B. Ribosomal_S4_B.
InterProiIPR022801. Ribosomal_S4/S9.
IPR001912. Ribosomal_S4/S9_N.
IPR005709. Ribosomal_S4_bac-type.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11831. PTHR11831. 1 hit.
PfamiPF00163. Ribosomal_S4. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01017. rpsD_bact. 1 hit.
PROSITEiPS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4FPJ3 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MARYTGPATR KSRRLKVDLV GGDQAFERRP YPPGQHGRAR IKETEYLLQL
60 70 80 90 100
QEKQKAKFTY GVLERQFRSY YEEANRRPGK TGDNLLQVLE CRLDNVVYRA
110 120 130 140 150
GLARTRRMAR QLVSHGHFTV NGKKVNIPSY QVSKWDIIDV KQKSLGTTPF
160 170 180 190 200
IIAKETIGER PVPAWLQVVP SNLRILVHQR PERAQIDTPV TEQLIVELYS

K
Length:201
Mass (Da):23,226
Last modified:April 17, 2007 - v1
Checksum:iB71671D6F613096B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM420293 Genomic DNA. Translation: CAM05968.1.
RefSeqiWP_009948669.1. NZ_ABFV01000057.1.
YP_001108893.1. NC_009142.1.

Genome annotation databases

EnsemblBacteriaiCAM05968; CAM05968; SACE_6804.
GeneIDi4946533.
KEGGisen:SACE_6804.
PATRICi23421050. VBISacEry28377_6807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM420293 Genomic DNA. Translation: CAM05968.1 .
RefSeqi WP_009948669.1. NZ_ABFV01000057.1.
YP_001108893.1. NC_009142.1.

3D structure databases

ProteinModelPortali A4FPJ3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 405948.SACE_6804.

Proteomic databases

PRIDEi A4FPJ3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAM05968 ; CAM05968 ; SACE_6804 .
GeneIDi 4946533.
KEGGi sen:SACE_6804.
PATRICi 23421050. VBISacEry28377_6807.

Phylogenomic databases

eggNOGi COG0522.
HOGENOMi HOG000221004.
KOi K02986.
OMAi TCKLSRR.
OrthoDBi EOG6N3CXM.

Family and domain databases

Gene3Di 1.10.1050.10. 1 hit.
3.10.290.10. 1 hit.
HAMAPi MF_01306_B. Ribosomal_S4_B.
InterProi IPR022801. Ribosomal_S4/S9.
IPR001912. Ribosomal_S4/S9_N.
IPR005709. Ribosomal_S4_bac-type.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view ]
PANTHERi PTHR11831. PTHR11831. 1 hit.
Pfami PF00163. Ribosomal_S4. 1 hit.
PF01479. S4. 1 hit.
[Graphical view ]
SMARTi SM00363. S4. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01017. rpsD_bact. 1 hit.
PROSITEi PS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338."
    Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F.
    Nat. Biotechnol. 25:447-453(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NRRL 23338.

Entry informationi

Entry nameiRS4_SACEN
AccessioniPrimary (citable) accession number: A4FPJ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: April 17, 2007
Last modified: October 29, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3