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A4FPF5 (A4FPF5_SACEN) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length378 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site391Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2671Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1371Substrate By similarity HAMAP-Rule MF_01201
Binding site3151Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue391N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
A4FPF5 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: FDF8433D813DB570

FASTA37840,423
        10         20         30         40         50         60 
MSDQHAHRAD LRIDVDAIRH NVGVLAARAA GARTMVIVKS DGYGHGTVTV ARAALEAGAG 

        70         80         90        100        110        120 
QIGVAALGEA VALREAGITA PLMCWLYSRG DDFAPALRHG VELSASSVRG LREIAATAAE 

       130        140        150        160        170        180 
LGLVARLHLK IDTGLCRSGC PEAEWPNLVD EAAKAEADGH VEVVAVWSHL ACADELGHPS 

       190        200        210        220        230        240 
IDNQALRFRR AYERARTAGL GPIRHLANSA AVLTRPDLHF EMVRPGIAVY GLDPVPQDGD 

       250        260        270        280        290        300 
HGLRPAMTFR SSVSLTKRVA AGESVSYGHT WTADRPVNLA LVPVGYADGV PRTLSGRMSV 

       310        320        330        340        350        360 
WLAGRRRPVV GRVCMDQLVV LCDDDVVREG DEVILFGPGD RGEPTAAEWA DELGTIHYEI 

       370 
VTGMYRPRVT RTVVGERA 

« Hide

References

[1]"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338."
Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F.
Nat. Biotechnol. 25:447-453(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NRRL 23338.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM420293 Genomic DNA. Translation: CAM05930.1.
RefSeqYP_001108855.1. NC_009142.1.

3D structure databases

ProteinModelPortalA4FPF5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING405948.SACE_6764.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAM05930; CAM05930; SACE_6764.
GeneID4946495.
KEGGsen:SACE_6764.
PATRIC23420970. VBISacEry28377_6767.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAITMDQLM.
OrthoDBEOG6PP9NJ.
ProtClustDBCLSK2536775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4FPF5_SACEN
AccessionPrimary (citable) accession number: A4FPF5
Entry history
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: February 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)