A4FPC1 (A4FPC1_SACEN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-hydroxy-3-oxopropionate reductase EMBL CAM05896.1
EC=1.1.1.60 EMBL CAM05896.1

Gene names

Ordered Locus Names:

SACE_6730

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL CAM05896.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate metabolic process Inferred from electronic annotation. Source: InterPro pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro valine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-hydroxy-3-oxopropionate reductase activity Inferred from electronic annotation. Source: EC 3-hydroxyisobutyrate dehydrogenase activity Inferred from electronic annotation. Source: InterPro coenzyme binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4FPC1 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: C8ADF763A5588D10	FASTA	292	29,484
	10 20 30 40 50 60 MTTIGFVGLG IMGSPMAANL VKAGYDVVGT NLTQDKIDLL VQQGGRGAAS IAEAVKDADV 70 80 90 100 110 120 VITMLPDSPD VDAAVLGEDG VFDHIRPGAL FIDCSSIRPD TSVKVAEAGA AKGVRVVDAP 130 140 150 160 170 180 VSGGEPKAID GTLSLMVGGE ADAFEAAKPI LEAVGTTIVH VGPAGSGQTV KIANQLIVAG 190 200 210 220 230 240 NIGLVAEALI FLEAYGVDTE AGLRALGGGL AGSTVLDAKG EKMRNREFSP GFRIELHNKD 250 260 270 280 290 LGNLEAAARG AGLALPIGAL VTQLIAAAKA QGDGKLDHSG LFKQIAQLSG RS

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAM05896.1.
RefSeq	YP_001108821.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4FPC1.
ModBase	Search...
Protein-protein interaction databases
STRING	A4FPC1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4946461.
GenomeReviews	Gene locus SACE_6730 in contig AM420293_GR.
KEGG	sen:SACE_6730.
PATRIC	23420904. VBISacEry28377_6734.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2084.
HOGENOM	HBG729179.
OMA	HKDMGIA.
PhylomeDB	A4FPC1.
Enzyme and pathway databases
BioCyc	SERY405948:SACE_6730-MONOMER.
Family and domain databases
InterPro	IPR002204. 3-OH-isobutyrate_DH-rel_CS. IPR015815. 3hydroxyacid_DH/Rdtase. IPR008927. 6-PGluconate_DH_C-like. IPR006115. 6PGDH_NADP-bd. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. IPR006398. Tartro_sem_red. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00042.
PANTHER	PTHR22981. 3hydroxy_acid_DH. 1 hit.
Pfam	PF03446. NAD_binding_2. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR01505. Tartro_sem_red. 1 hit.
PROSITE	PS00895. 3_HYDROXYISOBUT_DH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4FPC1_SACEN

Accession

Primary (citable) accession number: A4FPC1

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)