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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei136GTPUniRule annotation1
Binding sitei140GTPUniRule annotation1
Binding sitei184GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 22GTPUniRule annotation5
Nucleotide bindingi105 – 107GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSERY405948:SACE_RS27965-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:SACE_5835Imported
ORF Names:A8924_6177Imported
OrganismiSaccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)Imported
Taxonomic identifieri405948 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaeSaccharopolyspora
Proteomesi
  • UP000225825 Componenti: Unassembled WGS sequence
  • UP000006728 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi405948.SeryN2_010100004462

Structurei

3D structure databases

ProteinModelPortaliA4FLU4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 202TubulinInterPro annotationAdd BLAST193
Domaini204 – 321Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

A4FLU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPPHNYLAV IKVVGIGGGG VNAVNRMIEV GLKGVEFIAV NTDAQALLMS
60 70 80 90 100
DADVKLDIGR ELTRGLGAGA APEVGHKAAE DHKEEIEEVL KGADMVFVTA
110 120 130 140 150
GEGGGTGTGG APVIASVARK LGALTIGVVT RPFSFEGKRR ANQAEQGIKE
160 170 180 190 200
LRDCCDTLIV IPNDRLLQLG DIGVSLMDAF RSADEVLLSG VQGITDLITT
210 220 230 240 250
PGLINLDFAD VKSVMSGAGS ALMGIGSARG EGRAVQAAQK AINSPLLEAS
260 270 280 290 300
MEGAHGVLLA IAGGSDLGLF EINESASLVQ ESAHPEANII FGTVIDDSLG
310 320 330 340 350
DEVRVTVIAA GFDAGTPTHK KLEPTKVGSR DAVASGEAGR VTEGQVVGSK
360 370 380 390 400
PEPEPEPQQQ APTPPAPEPA AQQPAPPQPA PPPAPAQPEP QPEPQPQPPQ
410 420 430 440 450
QQAPAPAQHH EPERPQPQQE QRDNTDQRGG FAQRSPVFGG DGAGPSVSVP
460 470 480 490
TRAGGSGYPS HAGMSGSLPN RAVPVTDDND DDVDIPPFMR R
Length:491
Mass (Da):50,604
Last modified:April 17, 2007 - v1
Checksum:i1606188C62F54E11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM420293 Genomic DNA Translation: CAM05019.1
PDBV01000001 Genomic DNA Translation: PFG98656.1
RefSeqiWP_009943160.1, NZ_PDBV01000001.1

Genome annotation databases

EnsemblBacteriaiCAM05019; CAM05019; SACE_5835
KEGGisen:SACE_5835

Similar proteinsi

Entry informationi

Entry nameiA4FLU4_SACEN
AccessioniPrimary (citable) accession number: A4FLU4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: June 20, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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