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A4FKB4 (A4FKB4_SACEN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
Short name=Poly(P)/ATP NAD kinase HAMAP MF_00361
EC=2.7.1.23 HAMAP MF_00361
Gene names
Name:ppnK HAMAP MF_00361
Ordered Locus Names:SACE_5249
OrganismSaccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]
Taxonomic identifier405948 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361 SAAS SAAS002504

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP MF_00361 SAAS SAAS002504

Cofactor

Divalent metal ions By similarity. HAMAP MF_00361 SAAS SAAS002504

Subcellular location

Cytoplasm By similarity HAMAP MF_00361 SAAS SAAS002504.

Sequence similarities

Belongs to the NAD kinase family. HAMAP MF_00361

Sequences

Sequence LengthMass (Da)Tools
A4FKB4 [UniParc].

Last modified April 17, 2007. Version 1.
Checksum: 9288842B46FADB17

FASTA29731,410
        10         20         30         40         50         60 
MTRELLLVVH TGKQYNLRTA EKVAGQLLGA GIRVRVLAEE AAELDPACYT QAVKTGPLAA 

        70         80         90        100        110        120 
KGTELVLVLG GDGTLLRAAE LARMAQVPVF GVNLGRVGFL AGADSDALDE AVNAVVEGCY 

       130        140        150        160        170        180 
HVEERMTVEI TASLNGEILA TTWALNEASV EKSSRERILD VVIEVDGHPV SAFGCDGVLC 

       190        200        210        220        230        240 
STPTGSTAYA FSAGGPVVWP EVQALLVVPS NAHALFSRPL VVSRESLIAL EIAQNGHDAV 

       250        260        270        280        290 
LCCDGQRHFD LPAGARVEVV AGNTPVRLVR LHDTAFTDRL VGKFELPVQG WRGPVTD

« Hide

References

[1]"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338."
Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F.
Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM420293 Genomic DNA. Translation: CAM04489.1.
RefSeqYP_001107414.1. NC_009142.1.

3D structure databases

ProteinModelPortalA4FKB4.
SMRA4FKB4. Positions 3-292.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4FKB4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4945040.
GenomeReviewsGene locus SACE_5249 in contig AM420293_GR.
KEGGsen:SACE_5249.
PATRIC23417892. VBISacEry28377_5239.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0061.
HOGENOMHBG713904.
OMAGPVVWPE.
PhylomeDBA4FKB4.
ProtClustDBCLSK2536489.

Enzyme and pathway databases

BioCycSERY405948:SACE_5249-MONOMER.

Family and domain databases

HAMAPMF_00361. NAD_kinase.
[Tree]
InterProIPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017438. ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. polyP/ATP_NADK_prd.
[Graphical view]
Gene3DG3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KOK00858.
PANTHERPTHR20275. ATP_NADK. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA4FKB4_SACEN
AccessionPrimary (citable) accession number: A4FKB4
Entry history
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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