A4FG82 (A4FG82_SACEN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Name:	inhA EMBL CAM03057.1
Ordered Locus Names:	SACE_3786

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	252 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL CAM03057.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	151	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	A4FG82 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: F6E8FA082A0B1ACC	FASTA	252	26,602
	10 20 30 40 50 60 MLEGKRLLIT GVITDASIAF HAARVAQEQG AQVVLTGFGR LGLVERIAKR LPEPAPVIEL 70 80 90 100 110 120 DVTDQEHLDG LADKVREHAD GLDGVLHSIG FAPASCLGAP FLDAPWQDVS VALEVSAYSL 130 140 150 160 170 180 KSLTTAALPL LGEGSSVVGM DFDARVAWPA YNWMGVAKAA LESTNRYLAR ELGPKGIRVN 190 200 210 220 230 240 LVSAGPVRTM AAKSIPGFGE LEESWGTRAP LGWDVNDPTP VARSVCAVLS DWLPKTTGSM 250 IMVDGGVHAL GQ

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAM03057.1.
RefSeq	YP_001105982.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4FG82.
SMR	A4FG82. Positions 1-249.
ModBase	Search...
Protein-protein interaction databases
STRING	A4FG82.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4943607.
GenomeReviews	Gene locus SACE_3786 in contig AM420293_GR.
KEGG	sen:SACE_3786.
PATRIC	23414988. VBISacEry28377_3788.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0623.
HOGENOM	HBG750976.
OMA	KKWDGLD.
PhylomeDB	A4FG82.
ProtClustDB	PRK07889.
Enzyme and pathway databases
BioCyc	SERY405948:SACE_3786-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00208.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4FG82_SACEN

Accession

Primary (citable) accession number: A4FG82

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)