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Protein
Submitted name:

ATP-dependent DNA ligase

Gene

SACE_2706

Organism
Saccharopolyspora erythraea (strain NRRL 23338)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent DNA ligaseImported (EC:6.5.1.1Imported)
Gene namesi
Ordered Locus Names:SACE_2706Imported
OrganismiSaccharopolyspora erythraea (strain NRRL 23338)Imported
Taxonomic identifieri405948 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeSaccharopolyspora
ProteomesiUP000006728: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi405948.SACE_2706.

Structurei

3D structure databases

ProteinModelPortaliA4FD63.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000222509.
KOiK01971.
OMAiMHVRDPR.
OrthoDBiEOG661H49.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4FD63-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MLAETVGGRR VVLDGEVVAC DVRGRPDFGR LQTRISRTQP SPLLVRQVPA
60 70 80 90 100
VLLVFDLLMV DEVELLTVPY VERRERLAAL GLGGVGTVRM PEHYLDVTAE
110 120 130 140 150
QLLAVAREHD LEGIVAKRVQ SRYRPGQRSR EWIKTAIRHT TNAVVGGWVT
160 170 180 190 200
GSGAHRHVLG ALLLGVYGVD GRLHYAGHVG TGFSDRDRAV FAEGLAELAR
210 220 230 240 250
PTSPFADPVP RELARYAQWV EPLIVAEVEY RQWTDDGRLR HPAFRQLHPE

VTPASVRRP
Length:259
Mass (Da):28,820
Last modified:April 17, 2007 - v1
Checksum:i5EF55BC1EAD22040
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM420293 Genomic DNA. Translation: CAM01988.1.
RefSeqiYP_001104913.1. NC_009142.1.

Genome annotation databases

EnsemblBacteriaiCAM01988; CAM01988; SACE_2706.
GeneIDi4942537.
KEGGisen:SACE_2706.
PATRICi23412810. VBISacEry28377_2700.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM420293 Genomic DNA. Translation: CAM01988.1.
RefSeqiYP_001104913.1. NC_009142.1.

3D structure databases

ProteinModelPortaliA4FD63.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi405948.SACE_2706.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAM01988; CAM01988; SACE_2706.
GeneIDi4942537.
KEGGisen:SACE_2706.
PATRICi23412810. VBISacEry28377_2700.

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000222509.
KOiK01971.
OMAiMHVRDPR.
OrthoDBiEOG661H49.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338."
    Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F.
    Nat. Biotechnol. 25:447-453(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NRRL 23338Imported.

Entry informationi

Entry nameiA4FD63_SACEN
AccessioniPrimary (citable) accession number: A4FD63
Entry historyi
Integrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: January 7, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.