A4FCA2 (A4FCA2_SACEN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aldehyde dehydrogenase (NAD+) EMBL CAM01677.1
EC=1.2.1.3 EMBL CAM01677.1

Gene names

Name:	thcA EMBL CAM01677.1
Ordered Locus Names:	SACE_2377

Organism

Saccharopolyspora erythraea (strain NRRL 23338) [Complete proteome] [HAMAP]

Taxonomic identifier

405948 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Saccharopolyspora

Protein attributes

Sequence length	507 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344 EMBL CAM01677.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	aldehyde dehydrogenase (NAD) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4FCA2 [UniParc]. Last modified April 17, 2007. Version 1. Checksum: 98F3278256BFCDAA	FASTA	507	54,808
	10 20 30 40 50 60 MVLYAAPGAA GSVVEYRSRY DHFIGGEYVA PAGGEYFENP TPVTGKTFTE IARGTADDVE 70 80 90 100 110 120 RALDAAEGAA PAWGRTPAAE RAGVLLRIAD RMEHNLEKLA VAESWENGKP VRETLAADLP 130 140 150 160 170 180 LAIDHFRYFA GALRAQEGSI SQIDEDTVAY HFHEPLGVVA QIIPWNFPLL MATWKLAPAL 190 200 210 220 230 240 AAGNAVVLKP AEQTPASIHV LLDLIADLLP AGVLNVVNGF GVEAGKPLAS SPRVRKVAFT 250 260 270 280 290 300 GETTTGRLIL QYASQNIIPV TVELGGKSPN IFFDDVAAQQ DAFYDKALEG FTMFALNQGE 310 320 330 340 350 360 VCTCPSRALI QSGIYEGFLS DAVARTERIK QGNPLDTDTQ IGAQASNDQL EKILSYIDIG 370 380 390 400 410 420 RQEGAEVLTG GHRVELEGDL AGGYYVAPTI FQGHNNQRIF QEEIFGPVVS VAKFDDYADA 430 440 450 460 470 480 MNTANDTLYG LGAGVWSRNA GTAYRAGRDI QAGRVWVNNY HAYPAHAAFG GYKQSGIGRE 490 500 THKMMLDHYQ QTKNMLVSYS DNALGFF

References

[1]

"Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338." Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S., Haydock S.F., Leadlay P.F. Nat. Biotechnol. 25:447-453(2007) [PubMed: 17369815] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM420293 Genomic DNA. Translation: CAM01677.1.
RefSeq	YP_001104602.1. NC_009142.1.
3D structure databases
ProteinModelPortal	A4FCA2.
ModBase	Search...
Protein-protein interaction databases
STRING	A4FCA2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4942226.
GenomeReviews	Gene locus SACE_2377 in contig AM420293_GR.
KEGG	sen:SACE_2377.
PATRIC	23412166. VBISacEry28377_2377.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1012.
HOGENOM	HBG752218.
OMA	FIDKAAE.
ProtClustDB	CLSK735964.
Enzyme and pathway databases
BioCyc	SERY405948:SACE_2377-MONOMER.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00128.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4FCA2_SACEN

Accession

Primary (citable) accession number: A4FCA2

Entry history

Integrated into UniProtKB/TrEMBL:	April 17, 2007
Last sequence update:	April 17, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)